Protein Alignment Trpgamma and trpc3

DIOPT Version :10

• Sequence 1: NP_001137830.2
• Gene: Trpgamma / 34991
• FlyBaseID: FBgn0032593
• Length: 1188
• Species: Drosophila melanogaster
• Sequence 2: NP_001276813.2
• Gene: trpc3 / 101887082
• ZFINID: ZDB-GENE-140129-1
• Length: 902
• Species: Danio rerio
• Alignment Length: 902
• Identity: 343/902 - (38%)
• Similarity: 494/902 - (54%)
• Gaps: 140/902 - (15%)

  Fly    23 GADAADSAEKKLGSESSGSGHIAVQIE---PARRV-------KRHSIHG---MMEEENTIRPHQE 74
            |.||......|...||||.....::..   |.||:       :|.:|.|   |.....|
Zfish    31 GVDAHHLKSVKTVRESSGYYRYNMKSSESFPHRRMTLPREKGRRQAIRGPAFMFNARGT------ 89

  Fly    75 IRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLI 139
              .||.||::||.|.|.|::...|:||:::..   :||||:|.:|:..|.:|:.||:||:.|||:
Zfish    90 --SLTPEEERFLDAAEYGNIPVVRKMLEESLT---LNVNCMDYMGQNGLQLAVGNEHLEVTELLL 149

  Fly   140 NYN--VDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGN-------------HSWESASEDTST 189
            ..:  ....||||.:||:.:|..||.||.|.     |.||             ..:.|..||.:.
Zfish   150 RRDNLARVGDALLLAISKGYVRIVEALLGHP-----SFGNGERLTRSPCELQDDDFYSYDEDGTR 209

  Fly   190 FTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRAL 254
            |:|||||:|||||...||::.:||.:||.:..|||..|.|.:|.:.:::||..||||||||||.|
Zfish   210 FSPDITPIILAAHCQKYEVVHMLLLKGARIERPHDYFCKCADCTEKQRKDSFSHSRSRINAYRGL 274

  Fly   255 ASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEIL 319
            |||:.::|||:||:|||.|||.||.:|:.:|.||||:|::|..||:||...:||..|.:.|:|.:
Zfish   275 ASPAYLSLSSEDPVLTALELSNELAKLANIEKEFKNDYRKLSMQCKDFVVGVLDLCRDTEEVEAI 339

  Fly   320 LNHDPTGPVYEHGE--RMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAV 382
            ||.|.:..: |.|:  |..|:|:|||||...||||||.|.||.|.:||||.|.|.|.:..|::.:
Zfish   340 LNGDVSAEL-EEGQHHRSLLSRVKLAIKYEVKKFVAHPNCQQQLLTIWYENLSGLREQTTAVKCL 403

  Fly   383 DIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLML-ASQRIETFIGGWF 446
            .::.:.:..|:.::.|..||.|.:|:.:|.||:||:.|:||:..||.||:. ||.|.|
Zfish   404 VVLVVALGLPLLAVGYWFAPCSKLGKILRSPFMKFVAHAASFIIFLCLLVFNASDRFE------- 461

  Fly   447 FADSSGMLN----TMEELPTK-RGAKPTFIEW---LILAWVSGLIWSEVKQLWDVGLQEYLNDMW 503
                 |:..    |:.:.|.: ...|.|...|   ||:.||:|::|||.|:||..|.:||:..:|
Zfish   462 -----GITTLPNVTVTDHPLQIFRVKTTQFSWTEILIMVWVAGMMWSECKELWTEGPREYIMQLW 521

  Fly   504 NVIDFVTNSLYVATVALRVVSFFQVQKEMIY---NSHATDL--------------PRERWDAWDP 551
            ||:||...|:::|....|..:|.|..|...|   ..||.||              .|::|...||
Zfish   522 NVLDFGMLSIFIAAFTARFFAFMQAMKAQKYVDEKIHAPDLSMVTLPPDVRYFTYARDKWLPSDP 586

  Fly   552 MLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLL 616
            .||||||::.|.:.|..::.||...|...||||:||.|.|.||.||..|:::|..||..|:..|.
Zfish   587 QLISEGLYAIAVVLSFSRIAYILPANESFGPLQISLGRTVKDIFKFMVLFIMVFLAFMIGMFILY 651

  Fly   617 WYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDG 681
            .||..      .:|:|                    .|:.:.|:.:||||::|||.::.|..|..
Zfish   652 SYYLG------AKVNP--------------------AFTTVEESFKTLFWSIFGLSEVSSVVLKY 690

  Fly   682 IKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTC 746
            ...|....|.:::|.|:|..:|||||:||||:|.|||.|.:.|||||||||||||:|||:.|.|.
Zfish   691 DHKFIENIGYVLYGIYNVTMVVVLLNMLIAMINSSYQEIEDDADVEWKFARSKLWLSYFDNGKTL 755

  Fly   747 PPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLK---------------TIRRKAQQASD-- 794
            ||||:|:|:|||.:..:|.:..:.     ..||..||               ...:.:.:.:|
Zfish   756 PPPFSIVPSPKSFYLCVKRLVNLL-----RCRRRRLKKDVELGMDNSKSKLNLFTQSSMRMTDSH 815

  Fly   795 -------RDFKYQQIMRNLVRRYVTVEQRKAESQGVTEDDVNEIKQDISAFRCELVE 844
                   :..:|||||:.|::|||...|...|:..|.|.::.|||||||:.|.||:|
Zfish   816 SFNSILNQPTRYQQIMKRLIKRYVLKAQVDKENDEVNEGELKEIKQDISSLRYELLE 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trpgamma	NP_001137830.2	trp	77..841	CDD:273311	324/830 (39%)
		ANK repeat	118..147	CDD:293786	10/30 (33%)
		ANK repeat	175..217	CDD:293786	20/54 (37%)
		TRP_CaM_bind1	865..>891	CDD:467881
trpc3	NP_001276813.2	trp	78..869	CDD:273311	327/850 (38%)
		ANK repeat	128..159	CDD:293786	10/30 (33%)
		ANK repeat	206..241	CDD:293786	18/34 (53%)