Protein Alignment mtgo and myom1a

DIOPT Version :10

• Sequence 1: NP_001137829.1
• Gene: mtgo / 34987
• FlyBaseID: FBgn0259735
• Length: 2064
• Species: Drosophila melanogaster
• Sequence 2: NP_001154812.1
• Gene: myom1a / 558671
• ZFINID: ZDB-GENE-030131-2856
• Length: 1483
• Species: Danio rerio
• Alignment Length: 966
• Identity: 195/966 - (20%)
• Similarity: 312/966 - (32%)
• Gaps: 278/966 - (28%)

  Fly   915 DEEE-------YHRENSIIEQISAIEKPEVIDVT-SRAAKIIWESPAIANTVTVDMRQLRYQ--- 968
            :|||       |..|..:....:.|:|   .||: .|..    |:.::..||.|.....|||
Zfish   264 EEEELVERPHGYSPEYGVTFNTTIIDK---FDVSFGREG----ETMSLGCTVIVYPTVKRYQPEI 321

  Fly   969 ------VLLCDSGKQCKYKSL-YQGEAYECIVQDLQPGQDYLVRLQVHYQKLTGTVSDPTEFRTP 1026
                  |.|..|    |:..: :.||.....:..|....:.|..|:|:.:....|.|.....|..
Zfish   322 VWYRNGVALSSS----KWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVFVRDA 382

  Fly  1027 PCEPDQPPPPKLVSR----TKNSINLRWAAPAANGAS-IQHYLLEYDE------GRMPGQPQKFV 1080
            ..|.:..|...|..|    .|:.:.:.|..||..|:| |..|.::..|      .:....|.|:
Zfish   383 DVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKY- 446

  Fly  1081 ELAKIKAKHYVIGKLQPTTVYSFRLAAVNEAGQSPYS----PVASYSTS-------GNPPP---- 1130
                  |:..|.|.::..: |.||:.|:|.||.|..|    ||.:...|       |...|
Zfish   447 ------ARFPVTGLIEGRS-YMFRVRALNNAGVSRPSRVSDPVVAMDPSDRARLRAGPSAPWTGV 504

  Fly  1131 ------------VPKPPQLLA---SSSSSLKLGWERRAQDGDFLLQLQDAETGHGFLNTYKGTEL 1180
                        :|.||..||   ::.|.:.|.|:...|.|                  ::|...
Zfish   505 IKFTEEDPTVGVIPGPPTDLAVTEATKSYVVLSWKPPVQRG------------------HEGVMY 551

  Fly  1181 QTE-CL-----------------------QLRRASSYQFRLRSENEAGFSPWSPEVSYRTLAERP 1221
            ..| ||                       .|....||.||:||.|.||....|.|....|:.:|.
Zfish   552 YVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSEETGATTVGDRL 616

  Fly  1222 GRPGKPHAKGKIHGTQFKARWDAPSDSGGAEILCYHLELSAAGPAFERIYSGAETEAMCERLQPG 1286
            ..|..|.....|..|          ||  :.::|:                ||..|     ::..
Zfish   617 DLPSAPGPVIPIRNT----------DS--SVVVCW----------------GASKE-----VKDL 648

  Fly  1287 TTYALRACCEGPAGQSPYSDIGHVTTEAVPPSAPPPPHCSDPPSPYAALLKLRPPEYNGGAPILE 1351
            ..|.:....:|....:|                     |::.|.
Zfish   649 VGYYIEVTVDGSGVWAP---------------------CNNKPV--------------------- 671

  Fly  1352 FEAQMRRLEQVQPPQLVYRGKQTYFVAQDLTPGGMYETQVRAINRI---GAGSWSQWMRFTAAAA 1413
                                |.|.||...|........:|:|:|..   |:.:.|:.....|:.|
Zfish   672 --------------------KGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACLVKASIA 716

  Fly  1414 APGVPEELRVLVKSATHLGVSWQPPLQENGAPVTSYTLKSASQERKEDDSEEEVKEPPSSEFHNC 1478
            .|..|..:..|.:...::.:.||.|.:..||.:..|.|           ....||:..:|::|..
Zfish   717 VPSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYL-----------DYRTVKDGVTSKWHEL 770

  Fly  1479 YQGPQTCA--ELRNLSPYTRYHFRIQASNSAGTGNSSDVIS--VCT--PAAVPGAPQ-MQGYEFT 1536
            .....|.:  ::.:|.....|.|:::|.|.||...:|...:  .|.  ..||||.|. ::..|..
Zfish   771 NLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGPPHGLRVQEVR 835

  Fly  1537 AQEVTLNWTQPAAHG-SPICSYNIEYGE---RTIATPDACTRYT---VSGLMPETGYKFRVQAVN 1594
            ...:.:.|..|..:| ||:..|.:::.|   |.....:..|::|   ||||.....|:.|:.|.|
Zfish   836 KDSMVVLWEPPTFNGRSPVTGYYVDFKEENGRWRCVQERSTKHTYMKVSGLQEGISYRLRIHAKN 900

  Fly  1595 AIGAGAFSAYAKLTTQPAPPAPPRL--------------ECSGAGHNYIKLKWGENGNGKVVNSN 1645
            ..|.|..|...........|....:              |||....: .:..|.:|......:|.
Zfish   901 LAGVGVPSKATDAILAETRPGTNEIVVDVDDNGVISLIFECSDLKED-SQFVWSKNYEAFTDSSR 964

  Fly  1646 PS--GNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAHTDRAGDGDYSE 1708
            .:  ..||.....|.:..:.....:..|.:.|:.:...:.|.|.........:|..:.....:..
Zfish   965 LTIQTTGGKSRAIFNDPSLDDLGIYSCVVTNTDGVSASYTLTEEGLKRLLDISHDHQFPIIPFKS 1029

  Fly  1709 EFVFETSATLPANIKPPRVVQEGSVCLMELPGQLGMQLTLEWQHSKNSFNDRVEYE 1764
            |...|             :.::|.|......|:....|.:|:     .|||.|.:|
Zfish  1030 EMAIE-------------LQEKGRVRFWAEVGKFTSNLQVEY-----VFNDNVIHE 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mtgo	NP_001137829.1	FN3	<937..>1125	CDD:442628	52/213 (24%)
		FN3	1037..1124	CDD:238020	27/101 (27%)
		FN3	<1149..1216	CDD:238020	19/90 (21%)
		FN3	1221..1312	CDD:238020	13/90 (14%)
		FN3	1334..1409	CDD:238020	10/77 (13%)
		FN3	<1380..>1609	CDD:442628	59/245 (24%)
		FN3	1619..1714	CDD:238020	15/110 (14%)
myom1a	NP_001154812.1	Ig	167..260	CDD:472250
		Ig strand B	184..188	CDD:409353
		Ig strand C	197..201	CDD:409353
		Ig strand E	225..229	CDD:409353
		Ig strand F	239..244	CDD:409353
		Ig strand G	252..255	CDD:409353
		FN3	307..811	CDD:442628	129/639 (20%)
		FN3	823..914	CDD:238020	25/90 (28%)
		Ig	936..1006	CDD:472250	11/70 (16%)
		Ig strand C	949..953	CDD:409353	0/3 (0%)
		Ig strand E	974..978	CDD:409353	0/3 (0%)
		Ig strand F	988..993	CDD:409353	0/4 (0%)
		Ig	1381..1472	CDD:472250
		Ig strand B	1399..1403	CDD:319300
		Ig strand C	1412..1416	CDD:319300
		Ig strand E	1438..1442	CDD:319300
		Ig strand F	1452..1457	CDD:319300
		Ig strand G	1465..1468	CDD:319300