DRSC/TRiP Functional Genomics Resources

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Protein Alignment mtgo and Mybpc2

DIOPT Version :10

Sequence 1:NP_001137829.1 Gene:mtgo / 34987 FlyBaseID:FBgn0259735 Length:2064 Species:Drosophila melanogaster
Sequence 2:XP_038960733.1 Gene:Mybpc2 / 292879 RGDID:1311596 Length:1153 Species:Rattus norvegicus


Alignment Length:1089 Identity:205/1089 - (18%)
Similarity:345/1089 - (31%) Gaps:356/1089 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   880 NGNPQHPQRAGSSVGGASSVGTSEDGEDNSSLAGDDEEEYHRENSIIEQISAIEKPEVIDVTSRA 944
            |.:.:.|::..|   |.|.......|:..|..||:           ::....::|.||::...:.
  Rat   163 NVDVEAPRQDSS---GQSLESFKRSGDGKSEDAGE-----------LDFSGLLKKREVVEEEKKK 213

  Fly   945 AK---------IIWESPAIANTVTVDMRQLRYQVLLCDSGKQCKYKSLYQGEAYECIVQDLQPGQ 1000
            .|         .|||                    |....|:.:|:.:    |::..:.||:...
  Rat   214 KKDDDDLGIPPEIWE--------------------LLKGAKKSEYEKI----AFQYGITDLRGML 254

  Fly  1001 DYLVRLQVHYQKLTGTVSDPTEFRTPPCEPDQPPPPKLVSRTKN-SINLRWAAPAANGASIQHYL 1064
            ..|.:.:|..:|....    |:...|..:.|:....|||....: .:.|:|              
  Rat   255 KRLKKAKVEVKKSAAF----TKKLDPAYQVDRGNKIKLVVEISDPDLPLKW-------------- 301

  Fly  1065 LEYDEGRMPGQPQKFVELAKIKAKHYVIGKLQPTTVYSF------RLAAVNE---AGQSPYSPVA 1120
              :..|:                      :::|::.|.|      |:..:|:   |..:.|....
  Rat   302 --FKNGQ----------------------EIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAV 342

  Fly  1121 SYSTSGNPPPVPKPPQLLASSSSSLKLGWERRAQDGDFL-LQLQDAETGHGFLNTYKGTELQTEC 1184
            ..........|.:||.|:.:...      :::...||.: :.::.:|.|...:....|.|     
  Rat   343 KDEKCFTELFVKEPPVLIVTPLE------DQQVFVGDRVEMSVEVSEEGAQVMWMKDGVE----- 396

  Fly  1185 LQLRRASSYQFRLRSENEAGFSPWSPEVSYRTLAERPGRPGKPHAKGKIHGTQFKARWDAPSDSG 1249
              :.|..||:.|.|.:.:                      ||.|                     
  Rat   397 --MTREDSYKARYRFKKD----------------------GKRH--------------------- 416

  Fly  1250 GAEILCYHLELSAAGPAFERIYSGAETEA-------MCERLQPGTTYALRAC------CE----- 1296
               ||.|.......|..::.|.:|.:.||       ..|.||......::|.      ||     
  Rat   417 ---ILIYSDVAQEDGGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEK 478

  Fly  1297 ------------GPAGQSPYSDIG------------------------------------HVTTE 1313
                        .|:.:...|.:|                                    .:..|
  Rat   479 VTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVE 543

  Fly  1314 AVPPSAPPPPH--CSDPPSPYAALL----KLR---------PP--EYNGGAPILEFEAQMRRLEQ 1361
            .||...||..|  ||...|..:.::    |||         ||  .:..|..:........|:||
  Rat   544 YVPKQEPPKIHLDCSGKTSDNSIVVVAGNKLRLDVAITGEPPPTATWLKGDEVFTVSEGRTRIEQ 608

  Fly  1362 VQPPQLVYRGKQTYFVAQ--DLTPGGMYETQVRAINRIGAGSWSQWMRFTAAAAAPGVPEELRVL 1424
                    |...:.||.:  :.:..|.|  .::..|..|....|.::|   ....|..||.:|| 
  Rat   609 --------RPDCSSFVIESAERSDEGRY--TIKVTNPAGEDVASIFLR---VVDVPDPPEAVRV- 659

  Fly  1425 VKSATHLG-----VSWQPPLQENGAPVTSYTLKSASQERKEDDSEEEVKEPPSSEFHNCYQGPQT 1484
                |.:|     :.|:||..:.|.|||.|.:     |||:..|...:|       .|......|
  Rat   660 ----TSVGEDWAILVWEPPKYDGGQPVTGYLM-----ERKKKGSHRWMK-------LNFEVFTDT 708

  Fly  1485 CAELRNLSPYTRYHFRIQASNSAGTGNSSDVISVCTPAAVPGAPQMQGYEFTAQEV-----TLNW 1544
            ..|...:.....|..|:.|.|:.|....|.......|.|...|||    ..|.::|     ||.|
  Rat   709 TYESTKMIEGVLYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSAPQ----HLTVEDVTDTTTTLKW 769

  Fly  1545 TQPAAHGS-PICSYNIEY-----GERTIATPDACTR--YTVSGLMPETGYKFRVQAVNAIGAGAF 1601
            ..|...|: .|..|.:||     .|...|..:...|  :||..|.......|||..||..|....
  Rat   770 RPPDRIGAGGIDGYLVEYCLEGSEEWVSANKEPVERCGFTVKDLPTGARILFRVVGVNIAGRSEP 834

  Fly  1602 SAYAKLTT------QPAPPAPPRLECSGAGHNYIKLKWGE-------------------NGNGKV 1641
            :...:..|      ||....|..|.     ..||: |.||                   .|...:
  Rat   835 ATLLQPVTIREIVEQPKIRLPRHLR-----QTYIR-KVGEALNLVIPFQGKPRPQVVWTKGGAPL 893

  Fly  1642 VNSNPSGNGGDFTKYFVEMYVARAKQFQAVYSGTNCMCKVHKLQERSSYTFRIYAHTDRAGDGD- 1705
            ..|..:....||...|.....||:...:...|     .::..:::.::...|:   .::||..: 
  Rat   894 DTSRVNVRTSDFDTVFFVRQAARSDSGEYELS-----VQIENMKDTATIRIRV---VEKAGPAEN 950

  Fly  1706 YSEEFVFETSATLPANIKPPRVVQEGSVCLMELPG---QLGMQLTLEW-------QHSKNSFNDR 1760
            ...:.|:.|:|.:  ..:||:  .:|:   .|:.|   |...:.|:||       :|:..:.:|.
  Rat   951 VMVKEVWGTNALV--EWQPPK--DDGN---SEITGYFVQKADKKTMEWFNVYEHNRHTSCTVSDL 1008

  Fly  1761 VEYELQYAVLGAAELEGESLSPKGRSSSSSGSSNG---APINLPNHDYR 1806
            :.....|..:.:..:.|.|.||....:::.....|   .|:....||:|
  Rat  1009 IVGNEYYFRVFSENICGLSDSPGVSKNTARILKTGITLKPMEYKEHDFR 1057

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
mtgoNP_001137829.1 FN3 <937..>1125 CDD:442628 30/206 (15%)
FN3 1037..1124 CDD:238020 13/96 (14%)
FN3 <1149..1216 CDD:238020 11/67 (16%)
FN3 1221..1312 CDD:238020 20/156 (13%)
FN3 1334..1409 CDD:238020 18/91 (20%)
FN3 <1380..>1609 CDD:442628 63/246 (26%)
FN3 1619..1714 CDD:238020 18/114 (16%)
Mybpc2XP_038960733.1 Ig 66..166 CDD:472250 1/2 (50%)
Ig strand B 82..86 CDD:409554
Ig strand C 98..102 CDD:409554
Ig strand E 132..136 CDD:409554
Ig strand F 146..151 CDD:409554
Ig strand G 159..162 CDD:409554
THB 225..258 CDD:465725 9/56 (16%)
Ig 272..353 CDD:472250 15/118 (13%)
Ig strand B 286..290 CDD:409353 2/3 (67%)
Ig strand C 298..302 CDD:409353 2/19 (11%)
Ig strand E 323..327 CDD:409353 1/3 (33%)
Ig strand F 337..342 CDD:409353 1/4 (25%)
Ig strand G 346..349 CDD:409353 0/2 (0%)
Ig 360..446 CDD:472250 22/144 (15%)
Ig strand B 375..379 CDD:409353 0/3 (0%)
Ig strand C 387..391 CDD:409353 0/3 (0%)
Ig strand E 416..420 CDD:409353 3/27 (11%)
Ig strand F 430..435 CDD:409353 0/4 (0%)
Ig strand G 439..442 CDD:409353 0/2 (0%)
IG_like 459..>521 CDD:214653 6/61 (10%)
Ig strand B 468..472 CDD:409353 0/3 (0%)
Ig strand C 480..484 CDD:409353 0/3 (0%)
Ig strand E 505..509 CDD:409353 0/3 (0%)
Ig_C5_MyBP-C 562..647 CDD:409475 19/97 (20%)
Ig strand A 565..569 CDD:409475 0/3 (0%)
Ig strand B 573..580 CDD:409475 3/6 (50%)
Ig strand C 586..593 CDD:409475 1/6 (17%)
Ig strand C' 594..596 CDD:409475 0/1 (0%)
Ig strand D 604..610 CDD:409475 3/13 (23%)
Ig strand E 611..618 CDD:409475 2/6 (33%)
Ig strand F 626..634 CDD:409475 2/9 (22%)
Ig strand G 637..647 CDD:409475 3/12 (25%)
FN3 651..737 CDD:238020 28/102 (27%)
FN3 750..842 CDD:238020 26/95 (27%)
Ig_Titin_like 861..941 CDD:409406 13/85 (15%)
Ig strand A 861..865 CDD:409406 2/4 (50%)
Ig strand B 870..876 CDD:409406 0/5 (0%)
Ig strand C 882..888 CDD:409406 0/5 (0%)
Ig strand D 899..904 CDD:409406 0/4 (0%)
Ig strand E 905..911 CDD:409406 2/5 (40%)
Ig strand F 920..928 CDD:409406 1/12 (8%)
Ig strand G 931..941 CDD:409406 0/9 (0%)
FN3 946..1028 CDD:238020 17/88 (19%)
I-set 1060..1149 CDD:400151
Ig strand B 1077..1081 CDD:409353
Ig strand C 1090..1094 CDD:409353
Ig strand E 1115..1119 CDD:409353
Ig strand F 1129..1134 CDD:409353
Ig strand G 1142..1145 CDD:409353
Blue background indicates that the domain is not in the aligned region.

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