DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tpr2 and TPR14

DIOPT Version :9

Sequence 1:	NP_001260501.1	Gene:	Tpr2 / 34984	FlyBaseID:	FBgn0032586	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_201320.1	Gene:	TPR14 / 836639	AraportID:	AT5G65160	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	376	Identity:	111/376 - (29%)
Similarity:	181/376 - (48%)	Gaps:	43/376 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 EEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDP 114
            |..|.:||:.||..|:..||.||..||::.|:.|||..|::|....|.....|:.:.|.||||:|
plant   237 ETLKIMGNEDYKNGNFAEALALYDAAIAIDPNKAAYRSNKSAALTALGRILDAVFECREAIRIEP 301

  Fly   115 GFEKAYVRVAKCCLALGDI---------IGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATI 170
            .:.:|:.|:....|.||::         .|.|...:.:.:..::.|.: .:.|.|::||.....|
plant   302 HYHRAHHRLGNLYLRLGEVEKSIYHFKHSGPEADREDIAKAKTVQTHL-NKCTEAKRLRDWNGLI 365

  Fly   171 QANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVS---VMKLDTTS-- 230
            ....:|         :.|....||   :...|:||.|....|..|| |.|:|   |..:|.::
plant   366 TETTNT---------ISSGADAAP---QVYALQAEALLKTHRHQEA-DDALSRCPVFDIDASTRY 417

  Fly   231 ------ADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFK 289
                  |..:.||......:...|:.:...:||..||.::.:...:..:.:.:.|.:..||.|||
plant   418 YGPVGYAGFLVVRAQVHLASGRFDEAVEAIQRAGKLDGNNREVIMISRRAQAVTEARFKGNELFK 482

  Fly   290 SGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLL 354
            |||::||...|.:.|..|..    ||.||.|||...:::|...:::.||...|.:...|.||.|.
plant   483 SGRFQEACAAYGEGLDHDPR----NSVLLCNRAACRSKLGQFDKSIEDCTAALSVRPGYGKARLR 543

  Fly   355 RARCYNDLEKFEESVADYETALQLEKTPEIKRMLR---EAKFALKKSKRKD 402
            ||.|...:||:|.:|.|||  :..:::||.::::|   ||:..|.|...:|
plant   544 RADCNAKIEKWELAVGDYE--ILKKESPEDEQVIRGLSEAQQQLMKRSGQD 592

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_001260501.1	TPR_11	49..114	CDD:290150	26/63 (41%)
		TPR repeat	49..77	CDD:276809	12/26 (46%)
		TPR repeat	82..112	CDD:276809	10/29 (34%)
		TPR_11	201..262	CDD:290150	19/71 (27%)
		TPR repeat	201..225	CDD:276809	11/26 (42%)
		TPR_1	231..264	CDD:278916	8/32 (25%)
		TPR repeat	231..259	CDD:276809	6/27 (22%)
		TPR_11	278..345	CDD:290150	25/66 (38%)
		TPR repeat	310..344	CDD:276809	11/33 (33%)
		TPR_11	314..380	CDD:290150	25/65 (38%)
		TPR repeat	349..377	CDD:276809	13/27 (48%)
		DnaJ	401..>503	CDD:223560	1/2 (50%)
		DnaJ	402..469	CDD:278647	1/1 (100%)
TPR14	NP_201320.1	TPR_11	235..301	CDD:290150	26/63 (41%)
		TPR_2	236..268	CDD:285020	13/30 (43%)
		TPR repeat	236..264	CDD:276809	12/26 (46%)
		TPR	251..553	CDD:223533	90/319 (28%)
		TPR repeat	269..299	CDD:276809	10/29 (34%)
		TPR repeat	304..329	CDD:276809	5/24 (21%)
		TPR repeat	503..533	CDD:276809	11/29 (38%)
		TPR_1	507..537	CDD:278916	8/29 (28%)
		TPR repeat	538..562	CDD:276809	11/23 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D506649at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920