DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpr2 and TPR13

DIOPT Version :9

Sequence 1:	NP_001260501.1	Gene:	Tpr2 / 34984	FlyBaseID:	FBgn0032586	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_196571.1	Gene:	TPR13 / 830873	AraportID:	AT5G10090	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	376	Identity:	107/376 - (28%)
Similarity:	176/376 - (46%)	Gaps:	43/376 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 EEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMMLLNYNSALTDARHAIRIDP 114
            |..|.:||:.||..|:..||.||..|||:.|..|:|..|::|....|.....|:.:.|.||||||
plant   238 ETLKIMGNEDYKNGNFAEALALYEAAISIDPKKASYRSNKSAALTALGRILEAVFECREAIRIDP 302

  Fly   115 GFEKAYVRVAKCCLALGDI---------IGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLEATI 170
            .:.:|:.|:|...|.||::         .|.|...:.:::...:.|.: .:.|.|::||.....|
plant   303 HYHRAHHRLANLYLRLGEVENSIYHFKHAGPEADQEDISKAKMVQTHL-NKCTEAKRLRDWNTLI 366

  Fly   171 QANYDTKSYRNVVFYLDSALKL----APACLK-YRLLKAECLAFLGRCDEALDIAVSVMKLDTTS 230
            :...:|     :....|:|.::    |.|.|| ||..:|:  ..|.||      .|...::.|..
plant   367 KETENT-----ITTGADAAPQVYALQAEAFLKTYRHQEAD--DALSRC------PVFDGEMSTKY 418

  Fly   231 ADAIYVRGLCLYY------TDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFK 289
            ..:|...|..:.:      :....:.:...:||..||.::.:...:..:.:.:...:..||..||
plant   419 YGSIGYAGFLVVWAQVHMASGRFVEAVEAIQRAGKLDGNNREVSMVLRRAQAVTAARSRGNDFFK 483

  Fly   290 SGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLL 354
            :||::||...|.:.|..|..    ||.||.|||...:::|....||.|.:..|.:...|.||.|.
plant   484 AGRFQEACTAYGEGLDHDSR----NSVLLCNRAACLSKMGQFDRAVEDTSAALAVRPGYTKARLR 544

  Fly   355 RARCYNDLEKFEESVADYETALQLEKTPEIKRMLR---EAKFALKKSKRKD 402
            ||.|...|..:|.:|.|||  :..::|||.:.:::   ||:..|.|.:..|
plant   545 RADCNAKLGNWESAVGDYE--ILRKETPEDEEVIKGLSEAQKQLVKRRGHD 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_001260501.1	TPR_11	49..114	CDD:290150	26/63 (41%)
		TPR repeat	49..77	CDD:276809	12/26 (46%)
		TPR repeat	82..112	CDD:276809	9/29 (31%)
		TPR_11	201..262	CDD:290150	11/66 (17%)
		TPR repeat	201..225	CDD:276809	5/23 (22%)
		TPR_1	231..264	CDD:278916	6/38 (16%)
		TPR repeat	231..259	CDD:276809	4/33 (12%)
		TPR_11	278..345	CDD:290150	23/66 (35%)
		TPR repeat	310..344	CDD:276809	12/33 (36%)
		TPR_11	314..380	CDD:290150	25/65 (38%)
		TPR repeat	349..377	CDD:276809	12/27 (44%)
		DnaJ	401..>503	CDD:223560	1/2 (50%)
		DnaJ	402..469	CDD:278647	1/1 (100%)
TPR13	NP_196571.1	TPR repeat	237..265	CDD:276809	12/26 (46%)
		TPR_11	270..331	CDD:290150	19/60 (32%)
		TPR repeat	270..300	CDD:276809	9/29 (31%)
		TPR repeat	305..331	CDD:276809	6/25 (24%)
		TPR_11	473..536	CDD:290150	23/66 (35%)
		TPR repeat	473..499	CDD:276809	9/25 (36%)
		TPR repeat	504..534	CDD:276809	12/29 (41%)
		TPR_1	508..538	CDD:278916	9/29 (31%)
		TPR_16	517..573	CDD:290168	21/57 (37%)
		TPR repeat	539..563	CDD:276809	10/23 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D506649at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920