Protein Alignment Tpr2 and Rme-8

DIOPT Version :10

• Sequence 1: NP_523584.1
• Gene: Tpr2 / 34984
• FlyBaseID: FBgn0032586
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_610467.1
• Gene: Rme-8 / 35939
• FlyBaseID: FBgn0015477
• Length: 2408
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 82/427 - (19%)
• Similarity: 155/427 - (36%)
• Gaps: 108/427 - (25%)

  Fly   116 FEKAYVRVAKCCLALGDIIGTEQAVKMVNELN----SLSTAVAAEQTAAQKLRQLEATIQANYDT 176
            ::|..:.....|.|:|  :...::::.:.:|.    :..|.:..|...:.|:..:.....:.:.:
  Fly   998 WQKGLITPKTRCWAIG--MDGWRSLQQIPQLKWCLIAKGTPLYDETELSSKILDILIKCTSFFPS 1060

  Fly   177 KSYRNVVFYLDSALKLAPACLKYRLLKAECLAFL---------GRCDEALDIAVSVMKLDTTSAD 232
            ::...|      |:.:....|..:|.:..||..:         |..:....:...:|: |.....
  Fly  1061 RTQNGV------AVLIPGPKLSRKLSEFICLPHVVQVCLTHDPGLLERVATLLYQIME-DNPEMP 1118

  Fly   233 AIYVRGL---CLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKEN--GNMLFKS-- 290
            .:|:.|:   .|.||.:   .||...|.|.:  .|.|......:..|...|..:  |.:|.::
  Fly  1119 KVYLTGVFYFMLMYTGS---NILPITRFLKM--THMKQGFRSEETSQSGIMHRSILGQLLPEAMV 1178

  Fly   291 ----------------GRYREAHVIYTDAL------KIDEHNKDINSKLLYNRALVNTRIGNLRE 333
                            |.:....||::..:      ||..|..|...:|   |.....|...|..
  Fly  1179 CFLENYSAEKFAEIFLGEFDTPEVIWSSEMRRLLIEKIAAHIADFTPRL---RGHTMARYPYLAI 1240

  Fly   334 AVADCNRVLELNSQYLKALLLRARCYNDLEKFEE-SVADYETAL---------QLEKTP---EIK 385
            .|....: || |..:.....||..|  |.:||.. .::|....|         ::||.|   .|:
  Fly  1241 PVISYPQ-LE-NELFCHIYYLRHLC--DTQKFPNWPISDPVQLLKHTLDAWRKEVEKKPPQMTIQ 1301

  Fly   386 RMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFK 450
            :..::....|.|:.:.|            :..|:|:|.|.|.::|||::.|.       .|: |:
  Fly  1302 QAYQDLGIDLTKTPKPD------------ESMIRKSYYKLAQMYHPDKNPNG-------REI-FE 1346

  Fly   451 EVGEAYAILSDAHKKSRYDSGQDIEEQEQADFDPNQM 487
            :|.:||..|.   .::.:.||..         |||.:
  Fly  1347 KVNQAYEFLC---SRNVWSSGGP---------DPNNI 1371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_523584.1	TPR repeat	49..77	CDD:276809
		TPR	55..>258	CDD:440225	25/157 (16%)
		TPR repeat	82..112	CDD:276809
		TPR	190..419	CDD:440225	52/279 (19%)
		TPR repeat	201..225	CDD:276809	4/32 (13%)
		TPR repeat	231..259	CDD:276809	8/30 (27%)
		TPR repeat	310..344	CDD:276809	7/33 (21%)
		TPR repeat	349..377	CDD:276809	8/37 (22%)
		DnaJ_bact	402..>503	CDD:274090	21/86 (24%)
Rme-8	NP_610467.1	RME-8_N	12..835	CDD:466078
		GYF_2	972..1026	CDD:464112	4/29 (14%)
		DnaJ	1304..1356	CDD:395170	17/71 (24%)
		HEAT repeat	2174..2200	CDD:293787
		HEAT repeat	2212..2243	CDD:293787
		HEAT repeat	2253..2282	CDD:293787
		HEAT repeat	2291..2327	CDD:293787