Protein Alignment Tpr2 and dnajc3a

DIOPT Version :10

• Sequence 1: NP_523584.1
• Gene: Tpr2 / 34984
• FlyBaseID: FBgn0032586
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_955904.2
• Gene: dnajc3a / 322544
• ZFINID: ZDB-GENE-030131-1264
• Length: 504
• Species: Danio rerio
• Alignment Length: 494
• Identity: 133/494 - (26%)
• Similarity: 226/494 - (45%)
• Gaps: 32/494 - (6%)

  Fly    33 IDVKAEQI-VPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMML 96
            ||::.|.: ..||..  .|...::|.....|....:||..:..|:...|.:...:..||..|:.:
Zfish    22 IDLRYEGVNGGKDGG--VENHLEMGKKLLAAGQLADALSHFHAAVDGEPKNYMAFYRRATVYLAM 84

  Fly    97 LNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQ 161
            ....|||.|....|.:.|.|..|.::.....|..|.:...|...|.|.:.|..|......|:..:
Zfish    85 GKSKSALPDLSKVIELKPDFTSARLQRGNLLLKHGKLDEAESDFKKVLKSNPSSREEQEAQSQLK 149

  Fly   162 K---LRQLEATIQANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSV 223
            |   :::|.:..|:::..:.|.:...:||..:......:..|.::|||...:|...:|:....:.
Zfish   150 KSDEIQRLVSQAQSDFKHREYSSAASHLDIIIDTCVWDVDSREMRAECFIQMGELGKAISDLKAA 214

  Fly   224 MKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMK---ENGN 285
            .||.:.:..|.|......|...:.:..:......|.||.||   ||..|..||:|::.   ::..
Zfish   215 SKLKSDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDQDH---KQCFSHYKQVKKLNKQIQSAE 276

  Fly   286 MLFKSGRYREAHVIYTDALKIDEH--NKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQY 348
            .|.:..:|.:|...|...:|.:.:  :..:|:|......|  ::......|::.|:.||..:.|.
Zfish   277 ELIQQEKYSDAVSKYESVMKTEPNVPHFTLNAKERMCHCL--SKDQQTARAISVCSEVLNTDPQN 339

  Fly   349 LKALLLRARCYNDLEKFEESVADYETALQL-EKTPEIKRMLREAKFALKKSKRKDYYKILGIGRN 412
            :.||..||......:::||::.|:::|.:. |...:||..|..|:..||:||::|||||||:.|.
Zfish   340 VNALKDRAEALLQDDQYEEAIKDFQSAKEYSENDRQIKEGLERAQRLLKQSKKRDYYKILGVKRT 404

  Fly   413 ASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQ 477
            |...||.|||||.|...|||..  ..|||:|:.|.||.::.:|..:|:|...:|::|.|:|
Zfish   405 AQKKEILKAYRKLAQQWHPDNF--QDAEEKKKAEKKFIDIAQAKEVLTDPEMRSKFDQGED---- 463

  Fly   478 EQADFDPNQMFRTFFQFNGGGRN--------NSSFNFEF 508
             ..|.:..|.......|:||..|        :..|||:|
Zfish   464 -PMDPESQQGGGHHHHFHGGWENFQGFNPFGSGPFNFKF 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_523584.1	TPR repeat	49..77	CDD:276809	6/27 (22%)
		TPR	55..>258	CDD:440225	42/205 (20%)
		TPR repeat	82..112	CDD:276809	8/29 (28%)
		TPR	190..419	CDD:440225	62/234 (26%)
		TPR repeat	201..225	CDD:276809	5/23 (22%)
		TPR repeat	231..259	CDD:276809	3/27 (11%)
		TPR repeat	310..344	CDD:276809	7/33 (21%)
		TPR repeat	349..377	CDD:276809	8/27 (30%)
		DnaJ_bact	402..>503	CDD:274090	40/108 (37%)
dnajc3a	NP_955904.2	TPR repeat	37..65	CDD:276809	6/27 (22%)
		BepA	<38..104	CDD:443813	16/65 (25%)
		TPR repeat	70..100	CDD:276809	8/29 (28%)
		LapB	74..361	CDD:442196	66/291 (23%)
		TPR repeat	105..133	CDD:276809	6/27 (22%)
		TPR repeat	157..182	CDD:276809	5/24 (21%)
		TPR repeat	221..251	CDD:276809	4/29 (14%)
		TPR repeat	256..281	CDD:276809	7/24 (29%)
		TPR repeat	301..335	CDD:276809	7/35 (20%)
		TPR repeat	340..368	CDD:276809	8/27 (30%)
		TPR repeat	374..397	CDD:276809	10/22 (45%)
		PRK14277	392..>502	CDD:184599	44/117 (38%)