DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpr2 and dnajc3a

DIOPT Version :9

Sequence 1:NP_001260501.1 Gene:Tpr2 / 34984 FlyBaseID:FBgn0032586 Length:508 Species:Drosophila melanogaster
Sequence 2:NP_955904.2 Gene:dnajc3a / 322544 ZFINID:ZDB-GENE-030131-1264 Length:504 Species:Danio rerio


Alignment Length:494 Identity:133/494 - (26%)
Similarity:226/494 - (45%) Gaps:32/494 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 IDVKAEQI-VPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMML 96
            ||::.|.: ..||..  .|...::|.....|....:||..:..|:...|.:...:..||..|:.:
Zfish    22 IDLRYEGVNGGKDGG--VENHLEMGKKLLAAGQLADALSHFHAAVDGEPKNYMAFYRRATVYLAM 84

  Fly    97 LNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQ 161
            ....|||.|....|.:.|.|..|.::.....|..|.:...|...|.|.:.|..|......|:..:
Zfish    85 GKSKSALPDLSKVIELKPDFTSARLQRGNLLLKHGKLDEAESDFKKVLKSNPSSREEQEAQSQLK 149

  Fly   162 K---LRQLEATIQANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSV 223
            |   :::|.:..|:::..:.|.:...:||..:......:..|.::|||...:|...:|:....:.
Zfish   150 KSDEIQRLVSQAQSDFKHREYSSAASHLDIIIDTCVWDVDSREMRAECFIQMGELGKAISDLKAA 214

  Fly   224 MKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMK---ENGN 285
            .||.:.:..|.|......|...:.:..:......|.||.||   ||..|..||:|::.   ::..
Zfish   215 SKLKSDNTQAFYKLSTIYYDLGDHEMSLNEVRECLKLDQDH---KQCFSHYKQVKKLNKQIQSAE 276

  Fly   286 MLFKSGRYREAHVIYTDALKIDEH--NKDINSKLLYNRALVNTRIGNLREAVADCNRVLELNSQY 348
            .|.:..:|.:|...|...:|.:.:  :..:|:|......|  ::......|::.|:.||..:.|.
Zfish   277 ELIQQEKYSDAVSKYESVMKTEPNVPHFTLNAKERMCHCL--SKDQQTARAISVCSEVLNTDPQN 339

  Fly   349 LKALLLRARCYNDLEKFEESVADYETALQL-EKTPEIKRMLREAKFALKKSKRKDYYKILGIGRN 412
            :.||..||......:::||::.|:::|.:. |...:||..|..|:..||:||::|||||||:.|.
Zfish   340 VNALKDRAEALLQDDQYEEAIKDFQSAKEYSENDRQIKEGLERAQRLLKQSKKRDYYKILGVKRT 404

  Fly   413 ASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEEQ 477
            |...||.|||||.|...|||..  ..|||:|:.|.||.::.:|..:|:|...:|::|.|:|    
Zfish   405 AQKKEILKAYRKLAQQWHPDNF--QDAEEKKKAEKKFIDIAQAKEVLTDPEMRSKFDQGED---- 463

  Fly   478 EQADFDPNQMFRTFFQFNGGGRN--------NSSFNFEF 508
             ..|.:..|.......|:||..|        :..|||:|
Zfish   464 -PMDPESQQGGGHHHHFHGGWENFQGFNPFGSGPFNFKF 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpr2NP_001260501.1 TPR_11 49..114 CDD:290150 15/64 (23%)
TPR repeat 49..77 CDD:276809 6/27 (22%)
TPR repeat 82..112 CDD:276809 8/29 (28%)
TPR_11 201..262 CDD:290150 12/60 (20%)
TPR repeat 201..225 CDD:276809 5/23 (22%)
TPR_1 231..264 CDD:278916 6/32 (19%)
TPR repeat 231..259 CDD:276809 3/27 (11%)
TPR_11 278..345 CDD:290150 13/71 (18%)
TPR repeat 310..344 CDD:276809 7/33 (21%)
TPR_11 314..380 CDD:290150 16/66 (24%)
TPR repeat 349..377 CDD:276809 8/27 (30%)
DnaJ 401..>503 CDD:223560 40/109 (37%)
DnaJ 402..469 CDD:278647 31/66 (47%)
dnajc3aNP_955904.2 TPR repeat 37..65 CDD:276809 6/27 (22%)
TPR_11 38..102 CDD:290150 15/63 (24%)
TPR repeat 70..100 CDD:276809 8/29 (28%)
TPR_11 73..136 CDD:290150 16/62 (26%)
TPR_1 73..104 CDD:278916 9/30 (30%)
TPR repeat 105..133 CDD:276809 6/27 (22%)
TPR repeat 157..182 CDD:276809 5/24 (21%)
TPR_11 194..252 CDD:290150 11/57 (19%)
TPR repeat 221..251 CDD:276809 4/29 (14%)
TPR repeat 256..281 CDD:276809 7/24 (29%)
LcrH_SycD 262..389 CDD:274197 30/128 (23%)
TPR repeat 301..335 CDD:276809 7/35 (20%)
TPR repeat 340..368 CDD:276809 8/27 (30%)
TPR repeat 374..397 CDD:276809 10/22 (45%)
DnaJ 391..>502 CDD:223560 45/118 (38%)
DnaJ 394..459 CDD:278647 31/66 (47%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170592356
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53711
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R325
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
43.880

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