DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpr2 and Dnajc18

DIOPT Version :9

Sequence 1:	NP_001260501.1	Gene:	Tpr2 / 34984	FlyBaseID:	FBgn0032586	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	XP_006254608.1	Gene:	Dnajc18 / 291677	RGDID:	1310237	Length:	357	Species:	Rattus norvegicus

Alignment Length:	167	Identity:	51/167 - (30%)
Similarity:	74/167 - (44%)	Gaps:	49/167 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   358 CYNDLEKFEESVADYE-------------TALQLEKTPEIKRMLREAKFALKKSKRKDYYKILGI 409
            |.|.::..:|..::.|             |..||.....||             |.::||.|||:
  Rat    38 CCNCMKAQKEKKSENEWSQTRQGDGNATYTEEQLRGVQRIK-------------KCRNYYDILGV 89

  Fly   410 GRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDI 474
            ..||||:|:||||:|.||..|||::....|.:      .||.:|.|:|:||:..|:.|||...|.
  Rat    90 SHNASDEELKKAYKKLALKFHPDKNCAPGATD------AFKAIGNAFAVLSNPDKRLRYDEYGDE 148

  Fly   475 E--------------EQEQADFDPNQMFRTFFQFNGG 497
            :              ...:||..|.::|..||   ||
  Rat   149 QVTLTAPRARPYHYYRDVEADISPEELFNVFF---GG 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_001260501.1	TPR_11	49..114	CDD:290150
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		TPR_11	201..262	CDD:290150
		TPR repeat	201..225	CDD:276809
		TPR_1	231..264	CDD:278916
		TPR repeat	231..259	CDD:276809
		TPR_11	278..345	CDD:290150
		TPR repeat	310..344	CDD:276809
		TPR_11	314..380	CDD:290150	7/34 (21%)
		TPR repeat	349..377	CDD:276809	5/31 (16%)
		DnaJ	401..>503	CDD:223560	41/111 (37%)
		DnaJ	402..469	CDD:278647	30/66 (45%)
Dnajc18	XP_006254608.1	DnaJ	82..143	CDD:278647	30/66 (45%)
Dnajc18	XP_006254608.1	DUF1977	250..349	CDD:286411
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910