Protein Alignment Tpr2 and SPOM_SPBC543.02C

DIOPT Version :10

• Sequence 1: NP_523584.1
• Gene: Tpr2 / 34984
• FlyBaseID: FBgn0032586
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_596790.1
• Gene: SPOM_SPBC543.02C / 2541066
• PomBaseID: SPBC543.02C
• Length: 476
• Species: Schizosaccharomyces pombe
• Alignment Length: 497
• Identity: 180/497 - (36%)
• Similarity: 270/497 - (54%)
• Gaps: 60/497 - (12%)

  Fly    28 TEQPTIDVKAEQIVPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDS--AAYYGNRA 90
            ||..|..:.|.....::.|.:||::|.:||..||.:.|..|:|.||:||.|..||  |.||.|||
pombe     2 TEVETTHMNAGTESQQEPAELAEKQKAIGNAFYKEKKYAEAIKAYTEAIDLGSDSALAIYYSNRA 66

  Fly    91 ACYMMLLNYNSALTDARHAIRIDPGFEKAYVRVAKCCLALGDI------IGTEQAVKMVNELNSL 149
            |.||.:..:..||.||:.:.||.|...|...|:.:....|..:      :..:||...:|.|:.|
pombe    67 ATYMQIGEFELALCDAKQSDRIKPDVPKTQSRIRQAYEGLSILNEAEVYLKNKQAGLALNALDRL 131

  Fly   150 STAVAAEQTAAQKLRQLEATIQANYDTKSYRNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCD 214
            .             |::::|.|..                       :.:..|||:...|....|
pombe   132 Q-------------RRIDSTTQPP-----------------------MSWMYLKAQVYIFQNDMD 160

  Fly   215 EALDIAVSVMKLDTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKE 279
            .|..||..|::|:..:.:|:.:||..:||:....|.|.||:.||.||||...:|.:..:.::|:.
pombe   161 RAQKIAHDVLRLNPKNVEALVLRGKVMYYSGENAKAITHFQEALKLDPDCTTAKTLFKQVRKLEN 225

  Fly   280 MKENGNMLFKSGRYREAHVIYTDALKIDEHNKDINSKLLYNRALVNTRIGNLREAVADCNRVLEL 344
            .|..||.||:.|.|::|:..|::||:||..||:..:||..|||.|..|:....||::|.:..|.:
pombe   226 TKNQGNDLFRQGNYQDAYEKYSEALQIDPDNKETVAKLYMNRATVLLRLKRPEEALSDSDNALAI 290

  Fly   345 NSQYLKALLLRARCYNDLEKFEESVADYETALQLEKT-PEIKRMLREAKFALKKSKRKDYYKILG 408
            :|.|||.|.:||:.:..|||:||:|.|.::|::|:.: ..:::.||..:..||||||||:|||||
pombe   291 DSSYLKGLKVRAKAHEALEKWEEAVRDVQSAIELDASDANLRQELRRLQLELKKSKRKDHYKILG 355

  Fly   409 IGRNASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQD 473
            :.:.|:|.||||||||.|||:|||::|.:     .|.|.:||||||||.||||...:.|:|||.|
pombe   356 VSKEATDIEIKKAYRKLALVYHPDKNAGN-----LEAEARFKEVGEAYTILSDPESRRRFDSGVD 415

  Fly   474 IEE--QEQADFDPNQMFRTFFQ--------FNGGGRNNSSFN 505
            :|.  :..|..||..:.|.:..        |.|||....|:|
pombe   416 LEPGMEGGAGMDPFDILRAYQAGGSFPGGGFPGGGFPGGSYN 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_523584.1	TPR repeat	49..77	CDD:276809	13/27 (48%)
		TPR	55..>258	CDD:440225	60/210 (29%)
		TPR repeat	82..112	CDD:276809	14/31 (45%)
		TPR	190..419	CDD:440225	87/229 (38%)
		TPR repeat	201..225	CDD:276809	9/23 (39%)
		TPR repeat	231..259	CDD:276809	10/27 (37%)
		TPR repeat	310..344	CDD:276809	13/33 (39%)
		TPR repeat	349..377	CDD:276809	13/27 (48%)
		DnaJ_bact	402..>503	CDD:274090	51/110 (46%)
SPOM_SPBC543.02C	NP_596790.1	Spy	8..>275	CDD:443119	95/302 (31%)
		TPR repeat	23..51	CDD:276809	13/27 (48%)
		TPR repeat	56..88	CDD:276809	14/31 (45%)
		TPR repeat	93..117	CDD:276809	3/23 (13%)
		TPR repeat	146..171	CDD:276809	9/24 (38%)
		TPR	170..409	CDD:440225	106/243 (44%)
		TPR repeat	177..205	CDD:276809	10/27 (37%)
		TPR repeat	227..251	CDD:276809	10/23 (43%)
		TPR repeat	256..290	CDD:276809	13/33 (39%)
		TPR repeat	295..323	CDD:276809	13/27 (48%)
		PRK10767	345..>431	CDD:236757	50/90 (56%)