Protein Alignment Tpr2 and dnj-28

DIOPT Version :10

• Sequence 1: NP_523584.1
• Gene: Tpr2 / 34984
• FlyBaseID: FBgn0032586
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_491084.1
• Gene: dnj-28 / 171870
• WormBaseID: WBGene00001046
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 497
• Identity: 136/497 - (27%)
• Similarity: 218/497 - (43%)
• Gaps: 41/497 - (8%)

  Fly    38 EQIVPKDAATIAEEKKKLGNDQYKAQNYQNALKLYTDAISLCPDSAAYYGNRAACYMMLLNYNSA 102
            |.|...|..|.|:.:.:.||..:..:.|.:||..|..||.|.|........||..|:........
 Worm    13 EFIYSLDDKTEAQREYEAGNALFVNRQYSDALTHYHKAIELNPTMYQAIFRRATTYLAFGRSKPG 77

  Fly   103 LTDARHAIRIDPGFEKAYVRVAKCCLALGDIIGTEQAVKMVNELNSLSTAVAAEQTAAQKLRQLE 167
            |.|....:...|.|..|..:.|...|.:|.:   |:|......|...|.:....|.|.:||..:.
 Worm    78 LADLDTVLSQKPDFAGARQQRASVLLKMGQL---ERAAADFRYLIDHSASQETSQEAQEKLELIS 139

  Fly   168 ATIQANYDTKSY------RNVVFYLDSALKLAPACLKYRLLKAECLAFLGRCDEALDIAVSVMKL 226
            ..|......||:      .||:......|:..|......:.:|:|.....:...|:.......||
 Worm   140 EHINQVEMLKSWITNGDCNNVIESTTHLLETQPWDASLYIYRAKCYVAEDKVKSAIHDMKHAAKL 204

  Fly   227 DTTSADAIYVRGLCLYYTDNLDKGILHFERALTLDPDHYKSKQMRSKCKQLKEMKENGNMLFKSG 291
            .:.:.:.::......|...::...:......|.|:|||   |:..:..|.||::.::.:.:..|.
 Worm   205 SSDNTELLFEMSELEYKVADVRDSLGSIRECLKLNPDH---KKCYTSYKSLKKIVKSLDSMKASI 266

  Fly   292 RYREAHVIYTDAL----KIDEHNKDINSKLLYNRAL--VNTRIGNLREAVADCNRVLELNSQYLK 350
            ..:|    :|..|    |:.|.|::|..::...|.:  .|...|||.||:..|.||||.:...::
 Worm   267 EQQE----WTKCLETGEKLLEKNEEIPIRMNIFRLMCQCNREDGNLGEAIQQCTRVLEFDDSDVE 327

  Fly   351 ALLLRARCYNDLEKFEESVADYETALQLEKTPEIKRMLREAKFALKKSK----RKDYYKILGIGR 411
            .|:.||..|...|:::.::||||.|.:.:.:.:   .:|..|...|::|    ::|||||||:.|
 Worm   328 TLIQRAEAYMADEEYDMAIADYEKAEEWDSSND---AVRTGKDQAKRAKELVGKRDYYKILGVRR 389

  Fly   412 NASDDEIKKAYRKKALVHHPDRHANSSAEERKEEELKFKEVGEAYAILSDAHKKSRYDSGQDIEE 476
            ||:..||.|||||.|...|||...:.  :|:|:.|.||.::..|..:||:..|:..:|:|||..:
 Worm   390 NANKREITKAYRKMAQKWHPDNFQDE--KEKKKAEKKFIDIAAAKEVLSNEEKRRAFDNGQDPLD 452

  Fly   477 QEQ----ADFDPNQMFRTFFQFN------GGGRNNSSFNFEF 508
            .|.    .....:..|..|..||      ||||....|.|.|
 Worm   453 SEAGRGGGGGGGSHGFHNFHGFNPFGGGGGGGRGGGDFFFHF 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_523584.1	TPR repeat	49..77	CDD:276809	8/27 (30%)
		TPR	55..>258	CDD:440225	42/208 (20%)
		TPR repeat	82..112	CDD:276809	5/29 (17%)
		TPR	190..419	CDD:440225	62/238 (26%)
		TPR repeat	201..225	CDD:276809	3/23 (13%)
		TPR repeat	231..259	CDD:276809	1/27 (4%)
		TPR repeat	310..344	CDD:276809	13/35 (37%)
		TPR repeat	349..377	CDD:276809	10/27 (37%)
		DnaJ_bact	402..>503	CDD:274090	43/110 (39%)
dnj-28	NP_491084.1	NlpI	<23..>122	CDD:443815	25/101 (25%)
		TPR repeat	28..52	CDD:276809	7/23 (30%)
		TPR repeat	57..87	CDD:276809	5/29 (17%)
		TPR repeat	92..116	CDD:276809	6/26 (23%)
		LapB	167..>363	CDD:442196	47/205 (23%)
		TPR repeat	175..203	CDD:276809	3/27 (11%)
		TPR repeat	208..238	CDD:276809	2/29 (7%)
		TPR repeat	291..321	CDD:276809	11/29 (38%)
		TPR repeat	326..352	CDD:276809	9/25 (36%)
		DnaJ	380..445	CDD:395170	30/66 (45%)