DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tpr2 and dnajb12b

DIOPT Version :9

Sequence 1:	NP_001260501.1	Gene:	Tpr2 / 34984	FlyBaseID:	FBgn0032586	Length:	508	Species:	Drosophila melanogaster
Sequence 2:	NP_001082977.1	Gene:	dnajb12b / 100037354	ZFINID:	ZDB-GENE-070410-128	Length:	159	Species:	Danio rerio

Alignment Length:	196	Identity:	53/196 - (27%)
Similarity:	79/196 - (40%)	Gaps:	60/196 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 ERALTL------DPDHYKSKQMRSKCKQLKEMKENGNMLFKSGRYREAHVIYTDALKIDEHNKDI 313
            ||.:.:      |..|.|:::...|.::          ||.:.|.|       |.|:..|.|.
Zfish     9 ERCIDIAVEALEDSQHEKARRFLEKAQR----------LFPTHRAR-------DLLESLERNG-- 54

  Fly   314 NSKLLYNRALVNTRIGNLREAVADCNRVLELNSQYLKALLLRARCYNDLEKFEESVADYETALQL 378
                  |.:...:..|...|......|              |:...::.||..||...|
Zfish    55 ------NPSWSQSSAGGATEGTETHQR--------------RSGVSSNGEKPAESSKPY------ 93

  Fly   379 EKTPEIKRMLREAKFALKKSKRKDYYKILGIGRNASDDEIKKAYRKKALVHHPDR-HANSSAEER 442
              |||....:|..|      :.|:||:|||:.::||:|::||||||.||..|||: ||..:.|..
Zfish    94 --TPEQADAVRRIK------QCKNYYEILGVQKDASEDDLKKAYRKLALKFHPDKNHAPGATEAF 150

  Fly   443 K 443
            |
Zfish   151 K 151

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpr2	NP_001260501.1	TPR_11	49..114	CDD:290150
		TPR repeat	49..77	CDD:276809
		TPR repeat	82..112	CDD:276809
		TPR_11	201..262	CDD:290150	2/12 (17%)
		TPR repeat	201..225	CDD:276809
		TPR_1	231..264	CDD:278916	3/14 (21%)
		TPR repeat	231..259	CDD:276809	2/3 (67%)
		TPR_11	278..345	CDD:290150	12/66 (18%)
		TPR repeat	310..344	CDD:276809	5/33 (15%)
		TPR_11	314..380	CDD:290150	10/65 (15%)
		TPR repeat	349..377	CDD:276809	6/27 (22%)
		DnaJ	401..>503	CDD:223560	24/44 (55%)
		DnaJ	402..469	CDD:278647	23/43 (53%)
dnajb12b	NP_001082977.1	DnaJ	109..>151	CDD:278647	22/41 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910