Protein Alignment Nepl8 and ece2b

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_017206531.1
• Gene: ece2b / 793465
• ZFINID: ZDB-GENE-131120-140
• Length: 794
• Species: Danio rerio
• Alignment Length: 770
• Identity: 168/770 - (21%)
• Similarity: 272/770 - (35%)
• Gaps: 236/770 - (30%)

  Fly     4 ICLLLVPLVAASSNTRLLNGILSHVDKEANPCENYYNHACGQYNMRH-IDD------TFFDIIQM 61
            |||....:..||.       |:..:|:.|:||:::|.:|||.:..:: :.|      ||..|
Zfish    94 ICLTEACVTVASK-------IVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSI--- 148

  Fly    62 LDHQVNQNLVKLMDELEMSSQLPDFNVSS-VDGKVLRYYLSC--------RGAPRNMDSLSQYLK 117
                .:||...|...||..:    ||.|| .:.|...|||||        .||...||.:::.
Zfish   149 ----WDQNQAVLKHLLENGT----FNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKI-- 203

  Fly   118 VISPGEGLTWPQFIPDGSSWPQENF-KWLKALAHLHRYGLTNVFFNLEVVSNPRNAS-------- 173
               .|..:|        .||.:||| ..||.::..:|   ...||.:.|..:|:|::
Zfish   204 ---GGWNIT--------ESWDKENFLDVLKIISGPYR---AQPFFTVSVSVDPKNSNSNVIQVDQ 254

  Fly   174 ------------------------EYMVELNTPTFGEESQLPNSFIEIL---SVLYIIKVPSSEI 211
                                    :|||||.....|:::.......:||   :.|..|.||..|
Zfish   255 SGLFLPSRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDE- 318

  Fly   212 ITLARKMRTLELLLKTMINPIDTLNNRYISIRDFQ-METGHNWQRFFEILIGSSAAPELQ-VLVR 274
                  .|..|.:.            ..|:|.|.| :.....|..:...::......:.: |:|.
Zfish   319 ------RRDEEKIY------------HKITIADLQVLAPAIEWLDYLNSVLSPLELNDTEPVVVY 365

  Fly   275 NFRYFTALKELMDKQDARLVASYIM------------TRFAIF---LLDETMGGRES-----TEC 319
            ...|...:.||::|.|..|:.:|::            .||...   ||:...|.::|     ..|
Zfish   366 AKEYMQQVSELINKTDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTC 430

  Fly   320 VSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQ-------FLLQVDQNHLELTAL 377
            :......:..|...|:                :|..|:|...:       ||....:| :..|..
Zfish   431 IGNTDDTLGFALGALF----------------VKATFDKQSKEIDLNGGAFLPSCGRN-VNSTVH 478

  Fly   378 QMKF-FVRKAEAI--EINVVNLPKTDDLRHFIGQ-----------YYQDLQFP-----TGELD-- 421
            .:.| .:.:||.:  ||........|||:....|           .|..:.||     :.|||
Zfish   479 NLMFSVITQAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDV 543

  Fly   422 ----------YHQEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAPLPPPQ----------- 465
                      :.|..:....|..:.|..|..|..:.:|..:|..:..|...|.:
Zfish   544 YDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQ 608

  Fly   466 -PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRSH----RFEEAVSCL---- 521
             ||:..:......:..:|.:|.|.|..||..:|.....|||.:|:..:    .|:....|:
Zfish   609 APFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQY 673

  Fly   522 ---SRNSENID------ESMGDIAGLELAYFTYAK-MAKN--RNRLDFTHLPPEQIFFLNVGQFF 574
               :.|.|:|:      |::.|..||:.||..|.. :.||  ..||...:|..:|:||:...|.:
Zfish   674 TQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVW 738

  Fly   575 CGNSDMLVQYKEDQVRL-QRAIEGF------EPFDKAFGCYRNKP---KHEKCRL 619
            |            .||. :.|.||.      .|..:..|...|.|   :|.:|.|
Zfish   739 C------------SVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPL 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	159/739 (22%)
ece2b	XP_017206531.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010