Protein Alignment Nepl8 and Nepl21

DIOPT Version :10

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 744
• Identity: 168/744 - (22%)
• Similarity: 295/744 - (39%)
• Gaps: 180/744 - (24%)

  Fly     4 ICL---LLVPLVAAS--------SNTRLLNGIL---------SHVDKEANPCENYYNHACGQYNM 48
            ||:   :|..:|||:        .:|..:..:|         |.:|::|:||.::|..:||.|
  Fly    15 ICIAGHVLSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNY-- 77

  Fly    49 RHIDDTF------FDIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPR 107
            :.|:...      ..:.:.|...:|:.::|:::....|...|:      |.||..:|.||.....
  Fly    78 KRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTPE------DIKVKHFYESCLQIKE 136

  Fly   108 NMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHL-HRYGLTNVF---FNLEVVSN 168
            ...:.|:.||.:....| |.|  :.:||||.:::|.||...|.: :|||:|.:|   .|.::.||
  Fly   137 LNSTYSEKLKRLIAEFG-TMP--LLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLASN 198

  Fly   169 PRNASEYMVELNTPTFGEESQLPNSFIEILSVLY---------------------IIKVPSSEII 212
            .||    .:.|....|..|::  :.:::..:.:|                     :.|..:.|:|
  Fly   199 TRN----RIYLGQQDFPLEAR--SMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELI 257

  Fly   213 T--------LARKMRTLELLLKTMINPIDTLNNRYISIRDFQMETGHNWQRFFEILIGSSAAPEL 269
            .        |..:...|::...|.:..:|.:..||....|.        .|...:.:|...:.
  Fly   258 DFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRRYSPTLDI--------DRLLFVSMGERISD-- 312

  Fly   270 QVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDETMGG---RESTECVSQVR----RNM 327
            |:...|.||...|.|::.:...|.||:||..|. |:...||...   ::...||...:    :|:
  Fly   313 QIYEYNNRYQQNLVEVIKRTPKRTVANYIFFRL-IWEFVETPSDSPEKQMKACVDLTKKYFAKNL 376

  Fly   328 NLAANMLYKERFFEDSTFSANIL--EIKDIF-EKLRHQFLLQVDQNHLELTALQMKFFVRKAEAI 389
            :   ||.|:....|.|:...:.:  ::|..| |.||....|    |.:|.....:.....:|..:
  Fly   377 D---NMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSPAL----NWIERPTRNLAMAKLQAMTL 434

  Fly   390 EIN------------VVNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSS 442
            |:|            .:|| ::||       |.::::: |..|...|  ::.:..:..|.....|
  Fly   435 EVNNYADDNFTEEFAELNL-QSDD-------YVENVRY-TSLLGAKQ--MREMLHKPAKPFEAGS 488

  Fly   443 KGHSEEQNILTYRSQAAPLPPPQPFFQLESEDVFKYSLM----GYIMAHHLISAFATEGITIGSD 503
            :......|||...:...|:...|||:..  .||:..::|    ..::.|.||..|...|......
  Fly   489 QLSYTPANILIENTIKVPVALLQPFYIW--SDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEK 551

  Fly   504 GNDQSF----RSHRFEEAVSCLSR-----------------NSENIDESMGDIAGLELAYFTYAK 547
            ||.:.:    .|..|.:...|.::                 .||||    .|..|:.|||..|.|
  Fly   552 GNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENI----ADNGGMRLAYTAYRK 612

  Fly   548 MAKNRNRL-----DFTH--LP-----PEQIFFLNVGQFFCGNSDMLV--------QYKEDQVRLQ 592
            ..:|:..|     |.|.  ||     .:|:||::..|.:|.::...|        |:...:.|:.
  Fly   613 WYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPSVKALQVSTDQHMPGRFRVI 677

  Fly   593 RAIEGFEPFDKAFGCYRNKPKH--EKCRL 619
            .::..||.|.|.|.|......:  |||.|
  Fly   678 GSLSNFEEFSKEFNCPAGSAMNPSEKCIL 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	156/693 (23%)
Nepl21	NP_651646.2	M13	63..704	CDD:341056	155/692 (22%)