Protein Alignment Nepl8 and Nepl19

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651644.1
• Gene: Nepl19 / 43411
• FlyBaseID: FBgn0039612
• Length: 671
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 143/693 - (20%)
• Similarity: 267/693 - (38%)
• Gaps: 154/693 - (22%)

  Fly    11 LVAASSNTRLLNGIL---------SHVDKEANPCENYYNHACGQY-NMRHIDDTF---FDIIQML 62
            |::.|:::..:..::         |::.::|:.|||:|:::||.: .:...:|.:   .:.:|:|
  Fly    43 LISQSNDSAYVQRLMRLSKSAEMRSYMQQDADACENFYDYSCGNWPQINPANDAYPRETNFVQLL 107

  Fly    63 DHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLR---YYLSC---RGAPRNMDSLSQYLKVISP 121
            ....:....:||::        ..||.:.:..|||   :|.||   |..|.  |...:.|:.|..
  Fly   108 LKAYSHKQQRLMEQ--------PANVETDEVAVLRLKEFYASCLLFRQVPE--DLYRRQLQEIVA 162

  Fly   122 GEGLTWPQFIPDGSSWPQENFKWLKALAHLHR-YGLTNVFFNLE-----VVSNPRNASEYMVELN 180
            ..| ..|.....|..||.|.|.||..:|.:.| ||...:....:     .|..|:   :.:.|.|
  Fly   163 DFG-RMPVLSLPGQEWPAEEFDWLDTVARIKRQYGFDILLLFQQSADRIYVGQPK---QILPEAN 223

  Fly   181 TPTFGEESQLPNSFIEILSVLYIIKVPSS-EIITLARKMRTLEL-----LLKTMINPIDTLNNRY 239
            .....|:  :.|.....|.|...:.|.:: ||....:|:..:.:     ::..:..|.|.   .|
  Fly   224 RKAVAED--IANHLERHLGVDPKVAVTTAREITEFEQKIAAIMVDRRVGVMSKLYTPSDA---DY 283

  Fly   240 ISIRDFQMETGHNWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAI 304
            :.:...        .:|.|.::.........:......|...:.||:.:....::|:|:......
  Fly   284 VDVSKL--------TQFVETVLDRELLANESLYQHVPDYLMKIDELVTETPPHVLANYVFNELLK 340

  Fly   305 FLLDETMGGREST--ECVSQVRRNM-NLAANMLYKERFFEDSTFSANILEIKDIF---EKLRHQF 363
            ....|.   .||.  :|||:||... .|..:||: |::.::.|       :|||:   ::|:..|
  Fly   341 HFYYER---AESVVEQCVSRVRDLFGELLDHMLF-EQYEDEGT-------LKDIYVVWQQLQRSF 394

  Fly   364 --LLQ-------VDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGE 419
              :||       |.:...:|..             ::|..:|         :...|.::.|..
  Fly   395 RGVLQNSSANWLVPETREQLLE-------------QLNTTSL---------VINGYAEVNFTQ-- 435

  Fly   420 LDYHQEHLKVLQF----RTQKMLAQSSKGHSEEQNILTY----RSQAAPLPPPQPFFQLESE--- 473
             .|.:.|||...:    || .:..||.:...:.|..:||    :....|:...||.| |.|.
  Fly   436 -RYEELHLKPRDYLHNLRT-ILNHQSLRVKVKTQTSVTYDPVGKRVLLPVALLQPNF-LWSRYYP 497

  Fly   474 DVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRSHRFEEAVSCLSRNSENIDES------M 532
            ...:|..:|.::|..|..:.............:.|.|...|:|....|..|...:.||      :
  Fly   498 KAVRYGSLGTLLAQQLAHSLEDASKWDAKSFAEYSKRKSCFKEQYGRLRLNGHYLPESDLQAENI 562

  Fly   533 GDIAGLELAYFTYAKMAKNRNRLDFTHLPPE----------QIFFLNVGQFFCGNSDMLVQYKED 587
            .|...:::||..|.::..   .||.:.|..|          ::|||:..|.:|  :|...|:::.
  Fly   563 ADNLAIQVAYHAYRRLLA---ELDPSFLGSESLPQLNLGSRRLFFLSFAQLWC--NDANEQFRDK 622

  Fly   588 Q---------VRLQRAIEGFEPFDKAFGC--YRNKPKHEKCRL 619
            |         :|:..|:..|..|.:.|.|  .......:||:|
  Fly   623 QSLFLGTPNALRVLGALSNFRAFGRDFNCGTASRMTSPQKCQL 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	138/660 (21%)
Nepl19	NP_651644.1	PepO	67..657	CDD:226118	138/659 (21%)
		M13	73..664	CDD:189000	138/660 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840