Protein Alignment Nepl8 and Nep7

DIOPT Version :10

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651603.1
• Gene: Nep7 / 43356
• FlyBaseID: FBgn0039564
• Length: 717
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 154/721 - (21%)
• Similarity: 254/721 - (35%)
• Gaps: 191/721 - (26%)

  Fly    26 SHVDKEANPCENYYNHACGQY--------------NMRHIDDTFFDIIQMLDHQVNQNLVKLMDE 76
            |:::...:||:::|..|||.:              |:..|..|..|:.:.|     ....||.:.
  Fly    60 SYMNFSVDPCDDFYEFACGNWKNVKTPRQSPHRRSNILDISYTLMDVTEQL-----LTRTKLAEA 119

  Fly    77 LEMSSQLPDFNVSSVDGKVLRYYLSCRGA---PRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWP 138
            |.:|::|.         ...|:|.||..|   ||.... ..||.||....|  :|..  |..:|.
  Fly   120 LNVSAELL---------VAQRFYNSCLAAELFPRPAAD-PAYLSVIRSLGG--FPAV--DRDAWN 170

  Fly   139 QENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPN-SFIEILSVLY 202
            ..:|.|....|||..||:.::.....:..:|.|          |.|    :||. .|..::...:
  Fly   171 ASSFSWFNMSAHLSNYGVRSLIHEEILPQHPFN----------PYF----KLPELGFDHVVHTAH 221

  Fly   203 IIKVPSSEIITLARKMR-------TLELLLKTMINPIDTLNNRYISIRD-FQMETGH-------- 251
            :....|........:||       ..:..:..:|..:....:..:||.| |:.:...
  Fly   222 VANTSSRAYQLNEHRMRGYLKEYNLTKDEISAVIEGVFAFWSEALSIEDKFESDRDKCDLLSEIE 286

  Fly   252 ------NWQRFFEI-------LIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFA 303
                  .|:.::||       ..|||.......      |:..|.::..|. ...||:|:..||
  Fly   287 EVPRFGQWRSYYEIAWNGIDFYNGSSGGEFCDF------YYVELDKVCAKH-TEAVANYLAMRF- 343

  Fly   304 IFLLDETMGGRESTE-----CVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLR--- 360
            ::.:|:.:...:..|     |:..|:..:....|.||....|.|...|    ||.|:..::|
  Fly   344 LYRMDDKLKEPKQPEDQKVNCLMIVQMTLPNLFNRLYMAEHFTDEKHS----EISDMVTEMRKAQ 404

  Fly   361 HQFLLQVDQNHLELTALQMKFFVRKAEAIE-----INVVNLPKTDDLRHFIGQYYQDLQFPTGEL 420
            .|.|..|:....|          .:|||:.     ..|:...|.::|...:.:...:|....|..
  Fly   405 RQILESVEWLDAE----------TRAEALSKEAGITPVIGSYKNEELSDTLIREINNLTIVEGSY 459

  Fly   421 DYHQEHLKVLQFRTQKMLAQSSKGHSEE---------------QNILTYR------SQAAPLPPP 464
            .....:|:||    ...|.:.:..|::|               .|...|.      ..|..|.||
  Fly   460 AQSLINLRVL----GTYLHRYAGLHADELPKDTKPLTLLVGMQVNAFYYNLDNSVYVMAGVLHPP 520

  Fly   465 QPFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRSHR----FEEAVSC----- 520
            .  :.....|..|:..:||::.|.|...|.|||.:..|.|..:.:.|.:    |:|...|
  Fly   521 A--YHRSWPDSLKFGTIGYLIGHELTHGFDTEGSSFDSAGEVRDWWSRKSEAVFQERAQCYVDYF 583

  Fly   521 ----------LSRNSENIDESMGDIAGLELAYFTYAKMAKNRNR-----------------LDFT 558
                      ..|.:|..||::.|..||..|...|....|...|                 ||
  Fly   584 NQYLIPEINQTIRGNETRDENIADAGGLRAALTGYRNHMKQLQRSGADGETLAHKNEQMPGLD-- 646

  Fly   559 HLPPEQIFFLNVGQFFCGNSDMLVQYKE-------DQVRLQRAIEGFEPFDKAFGCYRNKPKH-- 614
             |.|||:||:...|.:|.:.:....::|       |:.|:..|:...:.|.:.:.|....|.|
  Fly   647 -LSPEQLFFVGFAQLWCADYEPEHYWEELTGAHTVDKYRVLGAVSNNDDFAEVYKCPLGSPMHPK 710

  Fly   615 -EKCRL 619
             |.||:
  Fly   711 AESCRM 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	151/712 (21%)
Nep7	NP_651603.1	M13	66..715	CDD:341056	151/712 (21%)