Protein Alignment Nepl8 and Nepl16

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001097912.1
• Gene: Nepl16 / 43014
• FlyBaseID: FBgn0039277
• Length: 752
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 131/708 - (18%)
• Similarity: 222/708 - (31%)
• Gaps: 300/708 - (42%)

  Fly    12 VAASSNTRLLNGILSHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQVNQNLVKLMDE 76
            ||:|...||        :...:||..:...:|.:                  :..|:|:..|
  Fly   163 VASSIQARL--------NWNKDPCTEFKKFSCWR------------------NTPNKNITNL--- 198

  Fly    77 LEMSSQLPDFNVSSVDGKVLRYYL------------------SCRGAPRN-------MDSLSQYL 116
            :||.:     :..|||.::|  ||                  ||.....|       .|||..||
  Fly   199 IEMGN-----SQKSVDSQML--YLFQNKIMNGSFGILHNLFESCLQQTTNSTVMHRIFDSLGGYL 256

  Fly   117 KVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYG---LTNVFFNLEVVSNPRNASEYMVE 178
            .|.|.|.....|                  .:|.::..|   |.:::.:|.....|.
  Fly   257 PVGSVGPSSIAP------------------LIAKIYDLGPSPLVDLYHDLSYGRRPH-------- 295

  Fly   179 LNTPTFGEESQLPNSFIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIR 243
                                 :|.||..||:....|.||:|
  Fly   296 ---------------------ILLIISGPSTSSTILERKIR------------------------ 315

  Fly   244 DFQMETGHNWQRFFEILIGSSAAPELQV----------LVRNF-RYFTALKELMDKQDARLVASY 297
                     |.        |..||..::          |:.|| .||.:..:.:.::|
  Fly   316 ---------WM--------SPKAPPSRIRQGVPKLLADLIENFLPYFVSYAQRVSEKD------- 356

  Fly   298 IMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQ 362
                 .||            |.:..:.:     ..:.:..|.|.|||...|:..::|::..|...
  Fly   357 -----TIF------------EFIKDLNK-----LQVEHSRRGFWDSTVLYNVSSLQDLYPVLNWT 399

  Fly   363 FLLQ-------VDQNHLELTALQMKFFVRK------------AEAIEI--------------NVV 394
            .|:.       |.:|...|.||:  :|:.|            ..|::|              .:.
  Fly   400 LLIPQNWSGPIVVRNSDYLKALE--YFLTKYPTRVAHNSLLLLSALQILPRDYPSPEVCTRSTMW 462

  Fly   395 NLPKTDDLRHFIGQYYQDLQFPT--GELDYH--QEHLK---------VLQFRTQKMLAQSSKGHS 446
            .||:.....:......:||:..|  .|:.:.  :.|||         :::....|:.:|:.:|.|
  Fly   463 ALPELSSSLYIAQHSSEDLKDTTKRAEIIFKSLKAHLKRAPSLKGAALVKLSALKIQSQTWEGFS 527

  Fly   447 EE------------------QNIL-TYRSQAAPLPPPQPFFQLESEDVFKYSLMGYI----MAHH 488
            ..                  |||| .|:..  .|.|........|.|.:.|.::..|    ::|.
  Fly   528 NTTDLLKSLQPLNITSECWFQNILEIYKKN--KLEPNDISLNGGSHDAWAYPIVSTIFYDTLSHS 590

  Fly   489 LISA------------------FATEGITIGSD---GNDQSFRSHRFEEAVSCLSRNSENI--DE 530
            ::..                  :|:.|::|..:   ...:||.    |:|:.|:. :|.||  :.
  Fly   591 IVVPLSVILIPYFNAVLPPYLHYASVGVSIAKEILRSITKSFD----EKAMRCVP-HSVNIFSNY 650

  Fly   531 SMGDI----AGLELAYFTYAKMA---KNRNRLDFTHLPPEQIFFLNVGQFFCGNSDML 581
            |..||    .|::::|.:...:.   |...||...:|.|.|||||...|..|..|:.|
  Fly   651 SRMDILIHSGGMQISYHSMLSLTGPIKGMARLPGLNLTPTQIFFLVSAQELCAESNYL 708

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	126/688 (18%)
Nepl16	NP_001097912.1	GluZincin	176..749	CDD:301352	126/687 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910