Protein Alignment Nepl8 and Nepl15

DIOPT Version :10

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651098.2
• Gene: Nepl15 / 42701
• FlyBaseID: FBgn0039024
• Length: 686
• Species: Drosophila melanogaster
• Alignment Length: 741
• Identity: 155/741 - (20%)
• Similarity: 273/741 - (36%)
• Gaps: 213/741 - (28%)

  Fly    10 PLVAASSNTRLLNGILSHV-----DKEANPCENYYNHACGQYNMRH------IDDTFFDIIQMLD 63
            ||.|..|...|.....:|:     |::...|.|:||:||..:...|      ....:.:.:|.|
  Fly    27 PLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQEL- 90

  Fly    64 HQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPRNMDSLSQYLKVISPGEGLTWP 128
                 .:.|..|.|:.:::..:   :|.|.::..:|.|||....:..|....|:.::...| .||
  Fly    91 -----YIRKSADMLKSATRGAE---NSADRQLKYFYGSCRLQTNDTRSALNTLQNVTDFRG-GWP 146

  Fly   129 QFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTF--------- 184
            :.  ..:||.|..:.||:.:|:|.|....::|..|||:.:.:....:.:::..|.|
  Fly   147 EI--RVASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRRHYLH 209

  Fly   185 ------------GEESQLPNSF--------IEILSVLYIIK------VPSSEIITLAR------- 216
                        ..|::|...|        .|:.|.:..|:      :|.:..:|||:
  Fly   210 PHFEGTREIYERSIENKLKLYFPEQSEHWRQEVASQVVQIEQQLAKGLPHNPALTLAQTTRQRTA 274

  Fly   217 -KMRT-----------LELLLKTMI------NPIDTLNNRYISIRDFQMETGHNWQRFFEILIGS 263
             :|:|           |:|:....:      .|.|.::|....||:
  Fly   275 AEMKTAYGSYVDVTRYLQLIFNDNLYMDLYETPEDYMSNLVDVIRE------------------- 320

  Fly   264 SAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMN 328
              .|:||  :.|:..:.||:.|   ..||:.||.                |....||       .
  Fly   321 --TPKLQ--LANYTMWKALEAL---DIARVPASQ----------------RADIWCV-------Q 355

  Fly   329 LAANMLYKERFFE---DSTFSAN------ILEIKDIFEKLRHQFL--LQVDQNHLELTALQMKFF 382
            ||      ::||.   :|.|..|      |.|::..:..::..|.  ||..:..|.||....:..
  Fly   356 LA------QQFFPHQLESLFHRNYNHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKA 414

  Fly   383 VRKAEAIEINVVNLPKTDDLRHFIGQYY-----QDLQFPTGELDYHQEHLKVLQFRTQKMLAQ-- 440
            :.|.||::::.    :|.|....|.|.:     .|..:|        ..:.|||::||:.||:
  Fly   415 ITKLEALKLHF----RTHDDNKLIRQMHGLILNMDRFYP--------NLVSVLQWKTQRGLAKLM 467

  Fly   441 -SSKGHSEEQNILTYRSQAAPLPPPQPFFQLE------SEDVFKYSLMGYIMAHHLISAFATEGI 498
             ......|...:..|..|...:..|..|.|..      ..:..||:.:|.::|..::..|...|.
  Fly   468 TEPVAEDEVHKLPHYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGR 532

  Fly   499 TIGSDGNDQSFRSHRFEEAVSCLSRNSENIDES---------------------MGDIAGLELAY 542
            ...:.|...::..|..|   |..||.::...|.                     :.|...|::||
  Fly   533 RYDAYGYKNNWWDHTSE---SSYSRRTQCFQEQYAIFVEYKGKPVQDKDLLRRIVADNGALDIAY 594

  Fly   543 FTYAKMAKN---------RNRLDFTHLPPEQIFFLNVGQFFCGN-SDMLVQYKE--DQVRLQRAI 595
            ..|.:..||         |.||........|||:|...|.:|.: .:.:.::.|  :|:|:..|:
  Fly   595 RAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTDYPETVERFDELPEQLRVNTAL 659

  Fly   596 EGFEPFDKAFGCYRNKPKHE--KCRL 619
            ...:.|..|:||.|.:..:.  ||.|
  Fly   660 SNSQQFANAYGCSREEKLNARFKCTL 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	146/711 (21%)
Nepl15	NP_651098.2	M13	56..684	CDD:341056	146/709 (21%)