Protein Alignment Nepl8 and Nepl14

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651097.1
• Gene: Nepl14 / 42700
• FlyBaseID: FBgn0039023
• Length: 696
• Species: Drosophila melanogaster
• Alignment Length: 666
• Identity: 145/666 - (21%)
• Similarity: 239/666 - (35%)
• Gaps: 178/666 - (26%)

  Fly    26 SHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSS 90
            |||:|..:||.::|.:|||.:.......      |.|..|.::.|:.|::|.          |..
  Fly    54 SHVNKSIDPCVDFYAYACGNWKSTLTPQ------QQLQQQTDRELLLLVEEA----------VRR 102

  Fly    91 VDGKVLR----YYLSCRGAPRNMDSLSQYL--KVISPGEGLTWPQFIPDGSSWP--QENFKWLKA 147
            .|..::|    .:.||..|..:.....|:.  :.|:...|  :|. :| ||.|.  ..::.||..
  Fly   103 EDSVIVRQAKELFKSCVSAQAHQSQQQQHFLSEFINQNGG--FPA-VP-GSQWAVHHHDYNWLSV 163

  Fly   148 LAHLH-RYGLTNVFFNLEVVSNPRNASE---YMVELNT--PT---FGEESQLPNSFIEILSVLYI 203
            |..|. |||: ::...|.|..|..|.:|   |:.|.:|  ||   ....|.:.:|..|.|.....
  Fly   164 LGGLRLRYGM-DILIGLRVGYNYGNVNENSLYLSEPSTLIPTELCTRNRSDIRDSIYEPLEHRVA 227

  Fly   204 IKVPS------SEIITLARKMRTLELLL-----KTMINPIDTLNNRYI------SIRDFQMETGH 251
            .::.|      .|...||..:.:.|..|     .......|.....|:      ::|:|......
  Fly   228 SELKSWLALGHDESARLAADILSFEHELCGGMKGGSFESWDAEEQLYLANYTRKTLREFSNSIEL 292

  Fly   252 NWQRFFEILIGSS-------AAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDE 309
            :...:.....|..       ||||         ||..||..:...:..|||:|||.| |:..|:.
  Fly   293 DLDSYVRASFGQDIYKPVYMAAPE---------YFRQLKRTVSAHNISLVANYIMYR-AVSALNF 347

  Fly   310 TMGGR---ESTECVSQVRRNMNLAANMLYKERF-FEDSTFSANILEIKDIFEKLR--------HQ 362
            .:..|   ...||:.:.:..:..|...||..:| .||..     :::.::::.|:        .:
  Fly   348 PLDDRPQLRKRECLERTKELLPTALGELYARQFGTEDGR-----IDLDNLYDTLKTALRQSLGAE 407

  Fly   363 FLLQ----VDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGELDYH 423
            :|::    |.|..|....|||..:.|            |....|:...|.|:|:|
  Fly   408 WLVEGTQRVGQEKLRNLKLQMPTYER------------PVILKLQLERGNYWQNL---------- 450

  Fly   424 QEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAPLPPPQ----------------------- 465
            ::.|.|:|              |:..|.|......||..|.:
  Fly   451 RQLLGVVQ--------------SQRNNRLFEEFLPAPTDPVEAYEARVRLRPVQRRLDMGLALLQ 501

  Fly   466 -PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGS------DGN---DQSFRSHRFEEAV-S 519
             |.:........:|:.:|..:|..|:.||.....::|.      ||.   ....||:.|...| :
  Fly   502 PPAYDPRYGHAIRYATLGVQLAQQLVMAFDDPHWSVGLLERDNWDGQTAWQYHIRSNCFARQVDN 566

  Fly   520 CLSRNSENIDESMGDIAGLEL---AYFTYAKMAKNRNRLDFTHLPPE---QIFFLNVGQFFCGNS 578
            .|..|.....:.:.|.|.:.:   ||.|:....:..|  |||.|..|   .:.:.|...||
  Fly   567 YLRPNVSATTQLITDSAAINVAFRAYLTWLGFQEPNN--DFTKLTKETLPDLNYSNTALFF---- 625

  Fly   579 DMLVQYKEDQVRLQRA 594
               :.|.::...|:.|
  Fly   626 ---LAYAQEHCSLEEA 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	141/660 (21%)
Nepl14	NP_651097.1	M13	60..693	CDD:189000	141/660 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469661
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840