Protein Alignment Nepl8 and Nepl13

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_651096.1
• Gene: Nepl13 / 42699
• FlyBaseID: FBgn0039022
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 156/747 - (20%)
• Similarity: 289/747 - (38%)
• Gaps: 211/747 - (28%)

  Fly    19 RLLNGILSHVDKEANPCENYYNHACGQ---YNMRHI-DDTFFDIIQMLDHQVNQNLVKLMDELEM 79
            ::...:..:::..|:||.:::.:||||   |:.|.: .|......|:::.::::.|.:|:.:...
  Fly    55 KIATDVQKYMNLSADPCTDFFEYACGQWGRYHKRQLRPDELSTAQQLMETKISEQLQQLLTQPLP 119

  Fly    80 SSQLPD-FNVSSVDG--KVLRYYLSCRGAPRNMDSLSQYL-KVISPGEGLTWPQFIPDGSSWPQE 140
            ....|: ::.:|:..  ||..:|.||.....|.....::| |::....||   :.:|: |:| |.
  Fly   120 PQHHPNGYSGASMTNVRKVRAFYESCVAVEANASERRRFLMKILKDNGGL---RNVPN-SNW-QH 179

  Fly   141 NFKWLKALAHLHR-YGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPNSFIEILSVLYII 204
            |.:|::.|..|.| ||| ::...||:..|.:.     ::.||..|||..         |::
  Fly   180 NRQWVQTLGELRRNYGL-DILLGLEIDLNLQT-----MKGNTIYFGEPK---------LTI---- 225

  Fly   205 KVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRD-FQMETGHNWQRFFEILIGSSAAPE 268
             :|:.....||.:...:...:..::....|.|     :|| |.|:||.. .||...:|
  Fly   226 -IPAEHCNALATRGAQVRDEVYELVQQQVTEN-----LRDWFGMDTGEA-ARFAGDII------- 276

  Fly   269 LQVLVRNFRYFTALKELMDKQD-------------ARLVASYIMTRFAIFLLDETMGGRESTECV 320
                    |:...|.:.|.:||             |::..:  .:|.....|....||...||..
  Fly   277 --------RFEFELCKQMGEQDIQKPEEEFPPAIQAQIYGA--RSRTGQERLRRQKGGMTLTELT 331

  Fly   321 SQVRRNMNLAANML--------YKERFFEDS---------TFSAN--------ILEIK------- 353
            |::..:::.  .||        |..:.:..|         |..||        ||.:.
  Fly   332 SEMGNHLDF--KMLVEVILESQYPSQVYLRSPEYVKHVVRTVKANNRITVGGYILYVALNELNQP 394

  Fly   354 -------------DIFEKLRHQFLLQVDQNHLE---------------LTALQMKFFV------- 383
                         .:.::|..|.|.::.|.|::               :.||:.:|.|
  Fly   395 PEEAPSQRARQCVQVTQRLFPQVLGEMFQRHVQRDNAKHDLDAVFNDVIKALEEQFHVEWMDEND 459

  Fly   384 RKAEAIEINV--VNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGH- 445
            |:|....::.  |:||....|.      ..||||...| ||.:.....|::|:.:.. ::.:|:
  Fly   460 RRAARTRLSQYRVSLPDYQSLD------LTDLQFQKSE-DYWRRLEIALKYRSHQQF-EALRGND 516

  Fly   446 --SEEQNILTYRSQAAPLPPPQ-----------PFFQLESEDVFKYSLMGYIMAHHLISAFATEG 497
              .:...:..:..:||..|..|           |::........||:|:|:.:|..|:.||..||
  Fly   517 FGQDADGLDAFEVRAALSPRQQMVLVGWGLLQAPYYNYYYPKSLKYALLGHRLASALVQAFDDEG 581

  Fly   498 -------------ITI-----GSDGNDQSFRSHRFEEAVSCLSRNSENIDESMGDIAGLELAYFT 544
                         :|:     .|:.....:.|:.:.|...  .||:..:.|.:.|.:||.||:..
  Fly   582 WNNHPQATAQWNEVTMSGYRNASECQRAQYSSYLYNEPGE--FRNATRLREIIADGSGLNLAFNA 644

  Fly   545 YAK------------MAKNR-NRLDFTHLPPEQIFFLNVGQFFC---GNSDM------LVQYKED 587
            |..            :||.. :.|:||:   .|:||:...|..|   .|.|.      |:|:..:
  Fly   645 YLAWLEQQDHKLRPLLAKETLSELNFTN---TQLFFIYFAQTRCWAKDNQDAILDSMPLMQHTPE 706

  Fly   588 QVRLQRAIEGFEPFDKAFGCYRNKPKH--EKC 617
            :..:...:.....|.:.|||....|.:  :||
  Fly   707 RWDVNGPLSNSAEFGREFGCALGTPMNSGDKC 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	156/734 (21%)
Nepl13	NP_651096.1	PepO	63..732	CDD:226118	153/731 (21%)
		M13	68..738	CDD:189000	154/732 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469668
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840