Protein Alignment Nepl8 and Nep4

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_650904.3
• Gene: Nep4 / 42449
• FlyBaseID: FBgn0038818
• Length: 1040
• Species: Drosophila melanogaster
• Alignment Length: 812
• Identity: 155/812 - (19%)
• Similarity: 266/812 - (32%)
• Gaps: 264/812 - (32%)

  Fly    27 HVDKEANPCENYYNHACGQYNMRH---IDDTFFDIIQMLDHQVN---QNLV-------------- 71
            ::|.:.:||.::|.:|||.:...|   .|...||..:||...::   :||:
  Fly   269 YMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRK 333

  Fly    72 ----------------------------------------------------------------- 71
                                                                             
  Fly   334 SPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETP 398

  Fly    72 ------------------KLMDELEMSSQL---PDFNVSSVDG--KVLRYYLSCRG----APRNM 109
                              |..|:.:...||   .||.....|.  |....|.||..    |.|.:
  Fly   399 RERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGL 463

  Fly   110 DSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASE 174
            :.|...::.:.     .||..   .|.|.:.||.|....|.|.||. .::.....|.::.:|:.|
  Fly   464 EPLHTLIRELG-----GWPVL---ESQWSESNFNWQVLAATLRRYN-NDILIVQWVGADIKNSEE 519

  Fly   175 YMVELNTPTFGEESQLPNS--FIE-------------ILSVLYIIKVPSSEIITLARKMRTLELL 224
            .:|:.:....|    ||..  |::             :..|::.:....::...:|.::...|..
  Fly   520 NIVQFDQTGLG----LPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQ 580

  Fly   225 LKTMINPIDTLNN-----RYISIRDFQMETGH-NWQRFFEILIGSSAAPELQVLVRNFRYFTALK 283
            |..:..|.:...|     :.:::...|..... .|:.:.:.|.........:|::....|.:.|.
  Fly   581 LAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYAVEYMSKLV 645

  Fly   284 ELMDKQDARLVASYIMTRFA---IFLLDE-----------TMGGRESTE-----CVSQVRRNMNL 329
            .|:|:.|.|.|::|:|.||.   |..:|:           .:.|||.:.     |::||..||.:
  Fly   646 TLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGM 710

  Fly   330 AANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVV 394
            |...::..|:|::::....:....|:.:..| ..|...|  .|:.|..|:      ||. ::|.:
  Fly   711 AVGSMFVSRYFDNNSKRDTLRMTHDLQQAFR-DILKTTD--WLDDTTKQL------AEE-KVNAM 765

  Fly   395 NLPKTDDLRHFIGQYYQDLQFPTGELD------------YHQEHLKVLQFRTQKMLAQSSKGHSE 447
            :|.        ||  |.|......||:            |.:..|.|| ..|.|  .:.:|.| |
  Fly   766 SLK--------IG--YPDFILNPSELNSKYAGIEIYPEKYFENTLNVL-LHTAK--TEQAKLH-E 816

  Fly   448 EQNILTYRSQAAP--------------------LPPPQPFFQLESEDVFKYSLMGYIMAHHLISA 492
            ..|...:  |.||                    |.|  ||:.........:..:|.::.|.|...
  Fly   817 RVNKTNW--QTAPAIVNAYYSRNKNQIMFPAGILQP--PFYHRHFPKSLNFGGIGVVIGHELTHG 877

  Fly   493 FATEGITIGSDGN------DQSFRSHRFEEAVSCLSRNSENI---------------DESMGDIA 536
            |..:|.....:||      |.|.|.  |:|...|:.....|.               .|::.|..
  Fly   878 FDDKGRLFDRNGNIHKWWTDSSIRG--FDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNG 940

  Fly   537 GLELAYFTYAKMAKNR------NRLDFTHLPPEQIFFLNVGQFFCG--------NSDMLVQYKED 587
            ||..|:..|.:..|..      ..|...::...|:||||.||.:||        |......:...
  Fly   941 GLRQAFHAYQRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPG 1005

  Fly   588 QVRLQRAIEGFEPFDKAFGCYRNKPKH--EKC 617
            :.|:...:.....|.:.|.|....|.:  :||
  Fly  1006 RFRVIGTLSNSVDFAREFNCPLGSPMNPQKKC 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	154/807 (19%)
Nep4	NP_650904.3	M13	274..1038	CDD:189000	154/807 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840