Protein Alignment Nepl8 and Nepl11

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 660
• Identity: 135/660 - (20%)
• Similarity: 236/660 - (35%)
• Gaps: 156/660 - (23%)

  Fly    18 TRLLNGILSH-----VDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQVNQNLVKLMDEL 77
            |.||:  .||     :|....||:::|.:.|.  :..::.:|        ..|..|:|:|..|
  Fly    26 TELLS--FSHNLEPYLDTSKQPCQDFYGYVCS--HSANLSET--------GRQRFQSLLKETD-- 76

  Fly    78 EMSSQLPDFNVSSVDGKVLRYYLSCRGAPRNMDSL--SQYLKVISPGEGLTWPQFIP---DGSSW 137
              .:||.|..:     :::.::.||... |.:::|  ||..:. |.|    ||...|   :.|..
  Fly    77 --VAQLMDMEL-----QLINFFKSCESG-RGVEALKGSQLYRQ-SGG----WPSLEPNKVNASQR 128

  Fly   138 PQENFKWLKALAHLHRYGLTNVFFNLEVV--SNPRNASEYMVELNTPTFGEESQLPNSFIEILSV 200
            ..:..:||..|.:.|..| ...||...|.  ||.|     :|.|. |.....:.|......:..|
  Fly   129 TNQTQRWLGLLGYFHEVG-APYFFETSVTMQSNKR-----LVVLQ-PDGTRRNTLRKFEQRVGEV 186

  Fly   201 LYIIKVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRDFQMETGHN-------WQRFFE 258
            |....:..|.....|.::.:||...:.::......:....|..:|:.....|       |..:|.
  Fly   187 LQSFGIEQSRAHVTALEVLSLERSRRDIVKADHVEDQVQFSYGNFKRIVFGNASLIRLDWDGYFR 251

  Fly   259 ILIGSSAAPELQVLV-----RNFRYFTALKELMDKQDARLV--ASYIMTRFAIFLLD-------E 309
            .|:|.........:|     |...||..|      |:..:|  .::|.|.:.:.::|       |
  Fly   252 KLLGGKTPQASDTIVVKQLPRLVEYFALL------QNTSMVRLLNWIWTDYLMDIVDADCHQLSE 310

  Fly   310 TMGGRESTECVSQVRRNMNLAANMLYKE--RFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHL 372
            |..|......|.:|..|....|.| |.|  :.:.|..  ...:.|.:|..:...|||
  Fly   311 TYAGDLYAHVVQRVTANRVELAQM-YSELGKAYTDQL--GGSVWIDEISRQSSRQFL-------- 364

  Fly   373 ELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKM 437
                              .|:::.....|.|  :...|..:......|..:.|.|:..| ||:::
  Fly   365 ------------------GNIMHTTLNGDER--LDAAYHSILLGRRSLYRNLEKLRKFQ-RTRRL 408

  Fly   438 LAQSSKGHSEEQNILTYRSQAAPLPPPQPFF-QLESEDVFKYSLMGYIMAHHLISAFA---TEGI 498
            .:.|:      |.:..|....||:   ..|. |........|.|:|...:..|::|.:   |:|.
  Fly   409 ASHSA------QQVRRYAQMFAPV---NAFLGQHNLSTPLNYLLLGEFFSRSLVAAGSSSRTQGA 464

  Fly   499 TIGSDGNDQSFRSHRFEEAVSCLSRNSENIDESMGDIAGLEL--AYFTY-AKMAKNRNRLD---- 556
            ...||.      ..||.....|:.:.:..||..:..:|..:.  ||..: |..|....|:|
  Fly   465 WRSSDS------ERRFAIFQQCVGKQTNAIDLLLSLLAQRQALSAYGQWLATQAGLVERVDAVLA 523

  Fly   557 --FTHLPPEQIFFLNVGQFFCGNSDMLVQYKEDQVRLQR---------AIEGFEPFDKAFGCYRN 610
              .:.:..:::||:         :.:||..:.:...||:         .:.....|.:||.|...
  Fly   524 AGSSKMSLQRLFFV---------TSLLVDCRSELGALQQDRKRQVTHATLRNSPEFLEAFRCRPG 579

  Fly   611 K---PKHEKC 617
            .   |:.::|
  Fly   580 DVLYPQDQRC 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	129/641 (20%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	128/637 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910