Protein Alignment Nepl8 and Nepl10

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 147/688 - (21%)
• Similarity: 273/688 - (39%)
• Gaps: 167/688 - (24%)

  Fly     5 CLLL---------VPLVA-ASSNTRLLNGILSHVDKEANPCENYYNHACGQY--------NMRHI 51
            ||||         :|:.| ...|....|.|.:::::..:||.|::|.|||::        |...:
  Fly     3 CLLLLCSCLVALFIPIQAIVDINVATSNDIHNNLNRTTSPCTNFWNFACGRFSSASKYVDNFERV 67

  Fly    52 DDTFFD-IIQMLDHQVNQN------LVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCR------ 103
            :|.|.. :::.::..:.:|      |:|.|.:                     ||.:|:
  Fly    68 EDQFATAMVEFMESHLGENDTLAPRLIKQMRQ---------------------YYKACKEDTRKL 111

  Fly   104 -GAPRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVS 167
             |.||..:.::|:  ::.|.:.|.                           |||..||.:..|..
  Fly   112 HGNPRPEELVNQW--ILHPKKFLV---------------------------YGLNGVFIDERVDV 147

  Fly   168 NPRNASEYMVELNTPTFGEESQLPNSFIEILSVLYIIKV-----PSSEIITLARKMRTLELLLKT 227
            ...::..::::|..|.       |........||.::::     .|..::.|..||..|:...:.
  Fly   148 AANDSMRWVIQLRMPD-------PADRYSDRRVLQLMRLYEEAWYSMGVVKLVEKMHQLQDKYRA 205

  Fly   228 MINPIDTLNNRYISIRDFQMETGHNWQRFFEILIGSSAAPELQVL---VRNFRY----FTALKEL 285
            ....:.|.:  :..:|. ::...|:   ||..|:|.:...||..|   |.:..|    |..|::.
  Fly   206 EYPVVYTWS--FSELRQ-EIPIPHS---FFIELLGVNHTEELYHLTFEVSDVEYLRECFRCLRDF 264

  Fly   286 -MDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKERFF----EDSTF 345
             .:.:|     :||..|..:.:.:.....|....|:..:|..:.|..|.:| :||.    |:.|
  Fly   265 ASEPKD-----TYIRARQYVLVEESEPRERNPRSCIHHMRAYLPLGMNYIY-DRFIYQNREEDT- 322

  Fly   346 SANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYY 410
             :.:|||....:....|:|   |.|.|:||..|:.:...|.|.|:|.:.|||: :....|...:|
  Fly   323 -SKVLEILSTLKAAFGQYL---DANRLQLTPNQLAYVRAKLEGIQIKIGNLPE-EKSPEFYNNHY 382

  Fly   411 QDLQFPTGELDYHQEHLKVLQFRTQ----KMLAQSSK-------------------GHSEEQNIL 452
            ....|  ...::....|:....||:    .:||::|:                   .:..|:|.:
  Fly   383 GSANF--SATNFLANLLEAFALRTRLQNAGLLARNSRVDLRHYYVNDNVRKARTSPFYENERNTI 445

  Fly   453 TYRSQAAPLPPPQ-PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSF-----RS 511
            |     .|:...| |.|......:|::||:|.::.|.:..||..|||...:.||:...     .|
  Fly   446 T-----VPMEFLQWPLFDHREHTIFQHSLLGAVLGHEMNHAFEQEGILFDAAGNESPVGLEIRES 505

  Fly   512 HRFEEAVSCLSRNS-ENIDESMGDIAGLELAYFTYAKMAKNRNRLDF------THLPPEQIFFLN 569
            ..|.:|:.|..... .::.|.:.|:.||:|||..:..:|.:..:.::      ......|:|.|:
  Fly   506 KPFRDAIKCAEEQPFVSLKERLADLNGLQLAYDAFFGLAHDSRQFEYRPYAFEQEFTAPQLFHLS 570

  Fly   570 VGQFFCGNSDMLVQYKEDQVRLQRAIEGFEPFDKAFGC 607
            ..|||||:...::.:..|..|:..::.....|...|.|
  Fly   571 YAQFFCGSLPPVIAHDRDDERVNVSVGNLRQFAYDFNC 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	138/651 (21%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	137/648 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910