Protein Alignment Nepl8 and Nepl7

DIOPT Version :10

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_609577.2
• Gene: Nepl7 / 34671
• FlyBaseID: FBgn0032442
• Length: 669
• Species: Drosophila melanogaster
• Alignment Length: 731
• Identity: 163/731 - (22%)
• Similarity: 272/731 - (37%)
• Gaps: 205/731 - (28%)

  Fly     1 MW--IICLLLVPLVAA--------SSNTR--LLNG----ILSHVDKEANPCENYYNHACGQYNMR 49
            :|  :|.|.|:..|.|        ::|.|  :|..    :||.:::..:||||:|..:||.:...
  Fly     5 LWATLISLTLIGRVLANDLFSLPPATNHREEMLEDYGRFLLSTMNRTIDPCENFYEFSCGGWKKA 69

  Fly    50 HI------DDTFFDIIQ-MLDHQVN---QNLVKLMDELEMSSQLPDFNV---SSVDGKVLRYYLS 101
            .:      :.:|.:.|| .:|.|:.   ||..|        .:|.|..|   :|.:.|..::|.|
  Fly    70 DLVPEQARNTSFLNAIQHKIDEQIQGFLQNATK--------RELEDLGVNGTTSAEIKAKQFYAS 126

  Fly   102 CRGAPRNMDSLSQYLKVISPGEGLTWPQFIP-DGSSWPQEN--FKWL-----------KALAHLH 152
            |.....|:....||              |:. ||....:.|  :.|:           ..||...
  Fly   127 CVEMKANLSLGYQY--------------FMEHDGDRLKERNATYDWMYINFMSKYDIYPLLALKV 177

  Fly   153 RYGLTNVFFNLEVVSNPRNA----SEYMVELNTPTFGEES--QLPNSFIEILSVLYIIKVPSSEI 211
            .|..::..|:: :::.|...    ||..::..|..||.:|  :....|:|..:
  Fly   178 HYSTSSRKFDI-LLTLPSKVLAGFSEEQLKNMTREFGLDSSAEKVKQFVENFN------------ 229

  Fly   212 ITLARKMRTLELLLKTMINPIDTLNNRYISIRDFQMETGH---NWQRFFEILIGSSAAPELQVL- 272
             .|.:..|.|..|.|:. |..:.||     .::|.::..|   ||.||||:....|......||
  Fly   230 -NLTQFERNLVSLAKSR-NETEQLN-----FKEFLVKHKHDRLNWTRFFELAFNGSQESHWPVLN 287

  Fly   273 ----VRNFRYFTALKELMDKQDARLVASYIMTR-----FAIFLLDETMGGRESTECVSQVRRNMN 328
                :.:..:|      :::.:...:..||..|     :.::......||.:| ||.|......|
  Fly   288 QLDNINDLVFF------LEQTNLETLKGYIKMRELVKFYGLWKTQTKTGGVQS-ECRSLSETYFN 345

  Fly   329 LAANMLYKERFFEDSTFSANIL----EIKDIF-EKLRHQFLLQVDQNHLELTALQMKFFVRKAEA 388
            .|....:..:.| |....|:||    :|||.| :.|.|...|..|      |..|.|   .|..:
  Fly   346 YALLPWFIGKVF-DKERRADILSVAKDIKDTFYDLLDHHTWLDED------TRSQAK---TKLAS 400

  Fly   389 IEINVVNLPKTDDLRH--FIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHSEEQNI 451
            ::|.|   ..||||:|  .|...|.|:.. ||.   ..|:|.:|:            |......:
  Fly   401 MDILV---GYTDDLQHREVIDGVYSDINM-TGN---WFENLCILE------------GSRARIRL 446

  Fly   452 LTYRSQAAPLPPPQ-----------------------PFFQLESEDVFKYSLMGYIMAHHLISAF 493
            .:......||..|.                       ||:.::..||.||:.:|.|:.|.:...|
  Fly   447 RSVDKALIPLLMPTRTVNAYYADFLNLAFITIGMAQWPFYHIDFPDVLKYAGVGNIIGHEMAHGF 511

  Fly   494 ATEGITIGSDGNDQSFRS----HRFEEAVSCL-------------SRNSENIDESMGDIAGLELA 541
            .:.......||...::.|    ..|:|...||             :..|....:::.|..|..:|
  Fly   512 DSYCYQYNYDGKKTNWWSSASLRNFKERYRCLESQYNKFILMGVQTNGSLTSGDNIADNVGTRMA 576

  Fly   542 YFTY-------AKMAKNRNRLDFTHLPPEQIFFLNVGQFFCG---NSDMLVQYKE-----DQVRL 591
            |:.:       |.:.|....::|.:   :|:||:...|.:|.   |.|.|.:.|.     |:.|:
  Fly   577 YYAFKRKTGDKAWLEKPLRGVNFNN---KQLFFVKFAQTWCNGKDNGDKLRRLKTDVHAYDEFRV 638

  Fly   592 QRAIEGFEPFDKAFGC 607
            |..:.....|.:||.|
  Fly   639 QGTLSNMPEFSEAFNC 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	152/684 (22%)
Nepl7	NP_609577.2	M13	52..666	CDD:341056	152/684 (22%)