Protein Alignment Nepl8 and Nepl6

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_609023.3
• Gene: Nepl6 / 33893
• FlyBaseID: FBgn0259716
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 668
• Identity: 272/668 - (40%)
• Similarity: 406/668 - (60%)
• Gaps: 63/668 - (9%)

  Fly     1 MWII-CLLLVPLVAASS--------NTRLLNGILSHVDKEANPCENYYNHACGQYNMRHIDDTFF 56
            ||:| ||.:||:.||.:        |:||:|.|||:|.::::.|..|:.:|||:|.:||.||.|.
  Fly     1 MWLIACLFIVPICAAPTTQNVEADPNSRLMNNILSYVAEDSSACGTYFQYACGKYAVRHRDDPFT 65

  Fly    57 DIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPRNMDSLSQYLKVISP 121
            :|||||||:||.|||:||.||...||.|.||.|||:.|||.:|.:||.||.:...:..||::..|
  Fly    66 EIIQMLDHKVNGNLVQLMHELHQRSQSPGFNESSVEAKVLHFYRTCREAPPSTRKMEHYLRLAPP 130

  Fly   122 GEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFGE 186
            |:.||||||:|.|..||:..|||:|:|.||:|||.|||..|:.|:.:..|::.:.::::.|:...
  Fly   131 GQALTWPQFMPRGEPWPKAQFKWMKSLGHLYRYGFTNVLVNVLVLRSSENSNRFRLDISMPSLEG 195

  Fly   187 ESQLPNSFIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRDFQMETGH 251
            ::|....|:..|:.|.||.||:..|:.|.||:|.||..::.:....|...:...::|.::.:||:
  Fly   196 DAQHLGGFLSTLATLQIIGVPTKSILPLVRKIRRLESAIRVLTEVDDDDESETWTLRQWEYKTGY 260

  Fly   252 NWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDETMGGRES 316
            .||.|.|.::|.|.:....:..:|.:|||.||.|||..||.:||:||||||.::|:|:.:...|.
  Fly   261 AWQGFVESIVGHSVSHHYVMQAQNAKYFTGLKRLMDSTDAEVVANYIMTRFVLYLIDDFIDSNEH 325

  Fly   317 TECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKF 381
            .:||:.:|||||||:|:||||||.:.:|......|:..:||:||.|||||:::|.|.||:.|...
  Fly   326 IDCVTDMRRNMNLASNLLYKERFLDPATLQQYTQEVTKVFEQLRRQFLLQINENRLGLTSEQNSM 390

  Fly   382 FVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHS 446
            ...||:.:.:|:.|||:..|.|.|:.::|:||.||..:.||.:|||.:|:|||:|.:.|
  Fly   391 VATKAQHVVLNIGNLPRGRDHRSFVSRHYEDLVFPLPDFDYAREHLNLLEFRTRKQVLQ------ 449

  Fly   447 EEQNILTYRSQAAPLPP--------------------------------PQPFFQLESEDVFKYS 479
                    .:|:||.|.                                .:|||..:|.|:||||
  Fly   450 --------LNQSAPTPDEFFYLSDPKTAMSSGPYYLMRLNIIVVPHGLLQEPFFAADSHDIFKYS 506

  Fly   480 LMGYIMAHHLISAFATEGITIGSDGN-----DQSFRSHRFEEAVSCLSRNS-ENIDESMGDIAGL 538
            |:|:::||.|:.:..|.|:.....||     .|...|.||...:.||:||| :.:||.:.|||||
  Fly   507 LLGFVLAHELMHSVDTVGLYYDRYGNIHEIGPQISSSPRFVAGLQCLNRNSTQYLDERIADIAGL 571

  Fly   539 ELAYFTYAKMAKNRNRLDFTHLPPEQIFFLNVGQFFCGNSDML--VQYKEDQVRLQRAIEGFEPF 601
            :|||.||.:.:...:..|||.:||:||||||:.|||||:.|.:  |.:..|:.|||:.:.||.||
  Fly   572 DLAYSTYFQNSSQMSLTDFTTIPPQQIFFLNLAQFFCGDGDPINFVGHDNDETRLQQMLNGFAPF 636

  Fly   602 DKAFGCYRNKPKHEKCRL 619
            .:||||.....:.|||:|
  Fly   637 HEAFGCPAKSNQPEKCQL 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	253/625 (40%)
Nepl6	NP_609023.3	M13	42..653	CDD:189000	253/624 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469638
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840