Protein Alignment Nepl8 and Nepl4

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_609019.1
• Gene: Nepl4 / 33889
• FlyBaseID: FBgn0031805
• Length: 652
• Species: Drosophila melanogaster
• Alignment Length: 684
• Identity: 163/684 - (23%)
• Similarity: 272/684 - (39%)
• Gaps: 126/684 - (18%)

  Fly     1 MWIICLLL--------VPLVA--------------ASSNTRLLNGILSHVDKEANPCENYYNHAC 43
            :|...|||        ||:.|              ::.|.:.::.::|:||.|.||||::|.:||
  Fly     5 LWTALLLLGSATCGSSVPVKANDPEQSCPYLGECNSTINQQHIDTLMSYVDSEKNPCEDFYAYAC 69

  Fly    44 GQYNMRHIDDTFFDIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPRN 108
            |::..:|...|...:|.  :.|:|:....|..:|..:...|::.. .:..|||.:|.||....:
  Fly    70 GKWRAKHGSHTTATMIS--ESQINRQYEDLFLQLLRNPSAPEYGY-PMFAKVLAHYQSCIALEK- 130

  Fly   109 MDSLSQYLKVISPGEGLTWPQFIPDGSSWPQEN-FKWLKALAHLHRYGLTNVFFNLEVVSNPRNA 172
             ..|.:|::::             |.......| ..|:..||.|.|||....:..:||  ...||
  Fly   131 -PDLRRYIELL-------------DRDLLASLNSTHWMHLLAALGRYGYHGHYVQVEV--RWYNA 179

  Fly   173 SEYMVELNTPTFGEESQLPNSFIEILSVLYIIKVPSSE-------IITLARKMRTLELLLKTMIN 230
            :.:|:.|          ||::....||:...|....|:       :..|..:.|:||..|..:..
  Fly   180 THHMIFL----------LPHNRHLNLSLTQDIYDALSQDGSSWPPLHQLQEQFRSLEQNLVRLAK 234

  Fly   231 P---IDTLNNRYISIRDFQMET-GHNWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDA 291
            |   .||..|  .|:...:.|. |.:|.......:|.|........|.:......|.|.::..|.
  Fly   235 PHSADDTFRN--YSLDQIRTEVPGLHWDEALRTQLGRSVPGNHVFQVDDLDAIEGLVEYLNTVDT 297

  Fly   292 RLVASYIMTRFAIFLLD---------ETMGGRESTECVSQVRRNMNLAANMLYKERFFEDSTFSA 347
            .|:..|.:.||...||:         |:........|:..:||::.|..|.:| ||.|......|
  Fly   298 LLLNRYSLARFLSHLLELPHNPLATWESGQRSRGRNCIRHMRRSVYLPMNYVY-ERSFYSRRRHA 361

  Fly   348 NILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYY-- 410
            :.|.|..:|::|:.|..|:|..|...|:...:|....|...:.|||.|||.     :...|:|
  Fly   362 DELVIHSVFQQLQSQLELRVQHNAFNLSQDLVKSLQAKVHQMRINVGNLPP-----NVTEQFYWD 421

  Fly   411 QDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAPLPP------------ 463
            .|.::..|. |:::.||..|.:....:....|....||::|....:...|..|
  Fly   422 SDRRWSVGR-DFYENHLNSLLYYYTLVADLESSSDQEERDIWYSFNMHTPEFPDNIDATPYFYCL 485

  Fly   464 -----------PQPFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGN-----DQSFRSH 512
                       .:|||.........|..:...:.|.::.||.|:.:...:.||     ||.....
  Fly   486 GNIIFVPYSYVKRPFFDANFWPALLYGDLANTLGHEIMHAFDTDLVDYDAQGNLRNFSDQLGEVE 550

  Fly   513 RFEEAVSCLSRNSENIDESMGDIAGLELAYFTYAK--MAKNRNRLDFTHLPPEQIFFLNVGQFFC 575
            .:..||.||:.::..::|...|::|..||..||..  :.::.|         .:::||....|||
  Fly   551 LYNGAVGCLNSSAVMLNERTSDVSGSRLAMQTYGGDWLTRSGN---------GRLYFLQFAHFFC 606

  Fly   576 GNSDMLVQYKED-QVRLQRAIEGFEPFDKAFGCY 608
            |  |...||.:. ..||..|:.....|.:.|.|:
  Fly   607 G--DEGDQYHDSGSQRLNYALGQVPQFAEVFRCH 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	151/631 (24%)
Nepl4	NP_609019.1	PepO	51..643	CDD:226118	155/638 (24%)
		GluZincin	59..649	CDD:301352	151/630 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.910