Protein Alignment Nepl8 and Nepl3

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_608904.1
• Gene: Nepl3 / 326172
• FlyBaseID: FBgn0031678
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 660
• Identity: 152/660 - (23%)
• Similarity: 285/660 - (43%)
• Gaps: 110/660 - (16%)

  Fly     2 WIICLLLVPLVAASSNTRLLNGILSHVDKEANPCENYYNHACGQYNMR-HIDDTFFDIIQMLDHQ 65
            |::.||...:.:|:.|..::..:|..:|::..||.|:||.:  |.|:: |...|..|..|:|...
  Fly    12 WLLLLLCSTVCSANPNLEIMKRMLDDMDEKVEPCHNFYNSS--QKNLKWHAFATVSDQFQLLFDG 74

  Fly    66 VNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPRNMDSLSQYLKVISPGEGLTWPQF 130
            :...:               |...|.:.|:.|.|..|....|  .||.:|.:::.|||.|.||..
  Fly    75 IENEV---------------FEKHSFEEKLQRLYKICSTMER--PSLLRYFELVKPGEDLNWPFL 122

  Fly   131 IPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPNSFI 195
            .|.|..||:|.|:|::|||.|.|||..::.|.:.:..:|.:.|...:.:....:       :|..
  Fly   123 TPRGGKWPKEKFQWMEALARLRRYGFNDIMFGMSIRQDPNSDSGQPIVVFEKKY-------DSLF 180

  Fly   196 EILSVLYIIKVPSSEIITLARKMRTLELLLKTMIN--------PIDTLNNRYISIRDFQMETGHN 252
            ..:..|..|.:|..    ||:::..|:..::.|..        ..|....:.||:...:: .|.:
  Fly   181 RFIESLQNIGLPPK----LAKEIAPLDNAIQEMYKSDMKFEHYARDAAPVKRISLGQLEI-YGVS 240

  Fly   253 WQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDETMGGREST 317
            ..::.||:.|...:|:..|.|.|..|...|:.||....:::||:|:..||:.:::...|  :...
  Fly   241 LTKYLEIVFGRPFSPDFVVHVENLYYLRGLQNLMTAVPSQVVANYLTARFSFYIMFTFM--KHGD 303

  Fly   318 ECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFF 382
            .||:.:|::|..|:|:|::||........:...:...||:.:|.|..:::::|.|:|...::...
  Fly   304 SCVTTMRQSMEFASNLLFEERILGRKKLRSYQNQAGKIFDAIRQQLNIRLERNVLKLPPAEISLL 368

  Fly   383 VRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHSE 447
            .:|...:.:::.|||.....|.|:.:||::|:|...| :....|||||:.||:..|:...:.:.:
  Fly   369 QKKLNGLSLSIGNLPGKAGHRRFVTRYYKELEFADDE-ELATAHLKVLEHRTRAELSLLDQPNFK 432

  Fly   448 EQNIL-------------TYRSQAAPLPPPQPF-----FQLESEDVFKYSLMG------------ 482
            ::..:             .|......:.....|     |..:|.|:||.:.:|
  Fly   433 DRRYMLHSYPISNFFFETAYEENGNTIYVAYDFLADASFDPDSHDIFKVTPLGIRFGLEMLKSFD 497

  Fly   483 -YIMAHH---LISAFATEGITIGSDGNDQSFRSHRFEEAVSCLSRNS--ENIDESMGDIAGLELA 541
             :...||   ::..|....||...|            |.||..::::  ...|:.:..:..:..|
  Fly   498 LFNCKHHKVNMLQLFDDNQITTAGD------------ECVSAWTQDNLLSQRDQYLVVLHLVHEA 550

  Fly   542 YFTYAKMAKNRNRLDFTHLPPEQIFFLNVGQFFCGNSDMLVQYKEDQVRLQRAIEGFEP------ 600
            ||........| :.:||.:...::||...||...|.:   :.:..|      .:||..|
  Fly   551 YFAEGSKFSQR-QPNFTTMSLRELFFFRFGQSSFGQT---LYFGSD------FVEGGSPINSLTR 605

  Fly   601 ---FDKAFGC 607
               |.:.|.|
  Fly   606 LPVFVRTFNC 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	145/630 (23%)
Nepl3	NP_608904.1	GluZincin	42..581	CDD:301352	136/585 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740