Protein Alignment Nepl8 and Nep6

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001245645.1
• Gene: Nep6 / 32234
• FlyBaseID: FBgn0030425
• Length: 655
• Species: Drosophila melanogaster
• Alignment Length: 694
• Identity: 154/694 - (22%)
• Similarity: 276/694 - (39%)
• Gaps: 130/694 - (18%)

  Fly     3 IICLLLVPLVAASSNTRLLNGILSHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQVN 67
            |:.::|:.|.||....:.|:   :..|.|..||||::.:|||.: ..:..........|....|.
  Fly    14 ILGVMLLKLAAAQDCQQQLD---NDTDAEVKPCENFHQYACGNW-YSNTSQRILGAHDMRSKWVA 74

  Fly    68 QNLVKLMDELEMSSQLPDFNVSS-----------------VDGKVLRYYLSCRGAPRNMDSLSQY 115
            ...::|:..||.||....|:.::                 :.|:.:|.|         .|:||:
  Fly    75 NLKLQLIRYLEESSSTDSFSANTSVTTSTAQLGTLYRCCLLSGQSIRTY---------TDALSR- 129

  Fly   116 LKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELN 180
                   .|..:|..    ::....:|.|:.|.|.|..||...: :.|.|..|.::|.:.:..:.
  Fly   130 -------SGANFPLL----ANHTGGSFDWVLANAALRTYGAQGL-WRLLVKDNWQSADQRIFYML 182

  Fly   181 TPTF---GEESQLPNSFI--EILSVLYI---IKVPSSEIITLARKMRTLELLLKTMINPIDTLNN 237
            .|.|   |.:.:| |.|:  ..|.:|.:   ::|..:.:  ||.|:...|..|:.:: |.|....
  Fly   183 PPKFDLLGRDDEL-NEFLYQRYLKILLLELGLRVRRAAL--LAEKLVAFEKSLQKLL-PNDAEQT 243

  Fly   238 RYI----SIRDFQMETGH-NWQRFFE-ILIGSSAAPELQVLVRNFRYFTALKELMDK--QDARLV 294
            ..:    |::|.:.:... ..:|:|| ||.|.....:..:||.:..|...|:.|:.:  .|..::
  Fly   244 LVLRKPQSLKDLESQLPRLELKRYFETILEGIDWDSKTLLLVADLDYLQGLQRLLAEHTSDPMVL 308

  Fly   295 ASYIMTR----FAIFLLDETMGGRESTECVSQVRRNM-----NLAANMLYKERFFEDSTFSANIL 350
            :::::.:    |.:.|.|:...|.:...|:.|:|:.|     .|...::..|.:  ...:...|.
  Fly   309 STWLLLQLPAYFELRLHDDDKLGNQRNHCLEQLRKLMPGQLGRLQMQLVLGESY--QDVYDTAIQ 371

  Fly   351 EIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVR-KAEAIEINVVNL-------PKTDDLRHFIG 407
            :|..:|..|:.||.|.:::..:....|..:...| |..|:.:....|       |.|..|.....
  Fly   372 QIAVLFRDLKQQFELVLNETEVFNEDLVTRNLARDKLRAMRLLTPRLQDPINGGPGTPQLGGNCD 436

  Fly   408 QYYQDLQFPTGELDYHQ-----------EHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAPL 461
            .....|.....:|:|.|           :.|.|..:...|:          .:..|.....|.||
  Fly   437 ANLLQLSLSQAKLEYRQVFGEPVTSVPADPLSVNAYYRLKL----------NRIELPLGLMATPL 491

  Fly   462 PPPQPFFQLESEDVFKYSL-MGYIMAHHLISAFATEGITIGSDG---NDQ-SFRS-HRFEEAVSC 520
            ...|  ...|::...|.|. :|||:||.::.||..:|:...:.|   |.| |.|: .||.....|
  Fly   492 IQQQ--CSKEADTRAKLSAGLGYILAHEMVHAFDLDGLNYDATGQLANGQWSARAIIRFGLRAGC 554

  Fly   521 -----LSRNSENIDESMGDIAGLELAYFTYAKMAKNRNRLDFTHLPPEQIFFLNVGQFFCG---N 577
                 .|..:..::|::.|..||.||..||      |:|...|:|   :.||:...|.:||   :
  Fly   555 YLGVRYSNATLTVNENIADTEGLRLALDTY------RHRSGATNL---RTFFVAFAQNWCGTVAS 610

  Fly   578 SDMLVQYKEDQVRLQRAIEGFEPFDKAFGCYRNKPKH--EKCRL 619
            :..|.|:.....|:...:.....|...|.|......:  .||.:
  Fly   611 TSGLSQHAGHAERVNNVVGNMPEFGDTFECKATSQMNPVNKCHI 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	145/662 (22%)
Nep6	NP_001245645.1	PepO	35..655	CDD:226118	148/670 (22%)
		M13	40..653	CDD:189000	145/662 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469654
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006719
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840