Protein Alignment Nepl8 and Nep1

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_001284925.1
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 728
• Identity: 149/728 - (20%)
• Similarity: 270/728 - (37%)
• Gaps: 190/728 - (26%)

  Fly    19 RLLNGILSHVDKEANPCENYYNHACGQYNMRH---IDDTFFDIIQMLDHQVNQNLVKLMDELEMS 80
            |....:||.:|..::|||:::.:|||.:|..|   .|.:.....::|.   :|..|.|...||..
  Fly   180 RTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLS---DQQQVILRAVLEEP 241

  Fly    81 SQLPDFNVSSVDGKVLRYYLSCRGAPRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWL 145
            ....| |.:::..|.  ::.||...|:        ::.|..|.   ..|.:.....||.....|.
  Fly   242 IDERD-NKATIKAKT--FFKSCMDIPQ--------IRKIGTGR---LKQVLQSLGGWPVIERNWS 292

  Fly   146 --------KALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFGEESQLPNSFIEILSV-- 200
                    :.:..|.......|...|.|.::.:|:|..:::::...:...|:  :.:::..|.
  Fly   293 PPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSR--DYYLKESSAND 355

  Fly   201 -----LYIIKVP---SSEIITLARKMRTLELLLKTMINPI-------DT-LNNRYISIRDFQ-ME 248
                 .|:.:|.   .::..|.|.::..:.|....::|..       || |..|.:.:.:.| :.
  Fly   356 RRAYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELV 420

  Fly   249 TGHNWQRFFEILIGSSAAPELQ----VLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFL--- 306
            ....||.:.:..:|...  .||    ::.....|.|.:.:::...|.|:|.:|::.|..:.|
  Fly   421 PEVQWQEYLQAALGPGI--PLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSH 483

  Fly   307 -LDE-----------TMGGRES----TECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDI 355
             :||           .||.:..    ::||....:.:.:|...|:                |:|.
  Fly   484 MIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALF----------------IRDN 532

  Fly   356 FEKLRHQFLLQVDQNHLELTALQMKFFVRKA--EAI--------EINVVNLPKTDDLRHFIGQYY 410
            |           :|...|: ||:|...:|.|  |.:        |...|...|.|.:...||  |
  Fly   533 F-----------NQESKEV-ALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIG--Y 583

  Fly   411 QDLQFPTGELDYHQEH--------------LKVLQFRTQKML----------------AQSSKGH 445
            .:|.....||:  ||:              |.:||:.::|||                |..:..:
  Fly   584 PELLTNATELE--QEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFY 646

  Fly   446 SEEQNILTYRSQAAPLPPPQP-FFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSF 509
            :..:|.:.:     |....|| |:.........|..:|.::.|.:...|..:|.....:||...:
  Fly   647 NPNKNDIVF-----PAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQW 706

  Fly   510 RSH----RFEEAVSCL----SRNSEN-ID----------ESMGDIAGLELAYFTYAKMAKNRNR- 554
            .::    .|.|...|:    ||...| :|          |::.|..||:.|:..|.|......|
  Fly   707 WNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGRE 771

  Fly   555 -----LDFTHLPPEQIFFLNVGQFFCGN---SDMLVQ-----YKEDQVRLQRAIEGFEPFDKAFG 606
                 |:.||   :|:||||..|.:||:   .|.|.:     :....||:...:.....|..|:.
  Fly   772 QQLPGLNMTH---DQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYK 833

  Fly   607 CYRNKPKH--EKC 617
            |......:  |||
  Fly   834 CPLGSTMNPAEKC 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	145/715 (20%)
Nep1	NP_001284925.1	M13	194..847	CDD:189000	145/714 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469686
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840