Protein Alignment Nepl8 and nep-24

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 609
• Identity: 118/609 - (19%)
• Similarity: 211/609 - (34%)
• Gaps: 133/609 - (21%)

  Fly     2 WIICLLL---VPLV--AASSNTR----------LLNGILSHVDKEANPCENYYNHACGQYNMRHI 51
            :::.|||   .||.  |.:..||          |.:.:.::.|...:||:|::..|||:   .|.
 Worm    13 FMLLLLLTCTAPLAIGATTPATRNVCNTPACITLAHMLHNYHDPSVDPCDNFHQFACGR---EHE 74

  Fly    52 DDTFFDIIQMLDHQVNQNLVKLMDELEMSSQLPDFNVSSVDGKVLRYYLSCRGAPRN-------- 108
            .:| .||.......:|..:.:.:.:.|.|.       |..:..:...|.:|:...:|
 Worm    75 HET-EDIYTKKTKTINNIMKRFLKKNETSR-------SKSENAMRTLYKACKTLEKNSTASRNKA 131

  Fly   109 MDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNV-FFNLEVVSNPRNA 172
            :..:.|.::.|.     .||  :.| ..|.:..|.....|.:|.|.|..|. .|.:....|.||.
 Worm   132 LQDIFQDIQSIG-----AWP--VVD-DKWDESKFDLNDFLVNLVRLGRKNFGLFQMARYVNVRNF 188

  Fly   173 SEYMVELNTPTFGEES------QLPNSFIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINP 231
            :          .|.|:      .|..:..|||.. ..::..:.:::....:...||..|..  :.
 Worm   189 A----------IGPEAAWRHNVDLGKTISEILKA-NSVQTNNKKLLDDLAEYVNLEKALSQ--HK 240

  Fly   232 IDTLNNRYISIRDFQMETGHNWQRFFEILIGSSAAPELQVL---VRNFRYFT----------ALK 283
            .:|:...||........:..|:.|    |:....:|:.:.|   |....|.|          .|:
 Worm   241 FNTVQPGYIFSERSDFVSSVNFSR----LVLEMMSPDKRTLFPEVYQIMYLTNTSLFFGKNNNLE 301

  Fly   284 ELMDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKERFFEDSTFSAN 348
            .::.....|.:|:|::.:|....:.:...|..|..|..:|...:..||...:...|...
 Worm   302 TIIRNTSKRALANYLIFKFIDTSIADLTYGSPSAFCEQKVINFLPRAALRAFYRNFISK------ 360

  Fly   349 ILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAE--AIEINVVNLPKTDDLRHFIGQYYQ 411
              |.:....||            .|.|.:|:...:...:  :|:...:.:.:...:...||  |.
 Worm   361 --ENRKKITKL------------TEATQVQLLKIIGATDWMSIKSKKIAMDRVSSMNMVIG--YP 409

  Fly   412 DLQFPTGELDYHQEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAA--PLPP----------- 463
            |...|.|:||...|||.:....|...:.:.......||.:..|..:..  ||.|
 Worm   410 DYFDPPGKLDGLFEHLNLSSSDTYYTVVRKINRFMREQEMDYYTGEVPYYPLFPGLMTNAMYNAN 474

  Fly   464 -----------PQPFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSF----RSHR 513
                       ..|||.....|....:.....:||.:...|:...:.| ..|..:.:    .:..
 Worm   475 DNNLMIFAPFFDDPFFDSSFPDYANIAFTSNTLAHEMGHTFSPHLMDI-MTGTTEVWLTPKETEE 538

  Fly   514 FEEAVSCL-SRNSENIDESMGDIA 536
            :|:.|.|| .:.:|..|...|.||
 Worm   539 YEKRVKCLEDQYTEYDDPEYGRIA 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	108/564 (19%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	106/561 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910