Protein Alignment Nepl8 and nep-6

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_494537.1
• Gene: nep-6 / 184628
• WormBaseID: WBGene00017550
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 130/717 - (18%)
• Similarity: 250/717 - (34%)
• Gaps: 205/717 - (28%)

  Fly    20 LLNGILSHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQV-NQNLVK---LMDELEMS 80
            |.:.:|:..|...:||:::|..|||:|:               :|:| |:.|.|   ::..:..:
 Worm    93 LADQLLNFQDPSVDPCQDFYKAACGKYS---------------EHEVANRRLQKKDIIIQRMIKN 142

  Fly    81 SQLPDFNVSSVDGKVLR-YYLSCRGAPRNMDSLSQYLKVISPGEGLTWPQFIPD---GSSWPQEN 141
            ..|.:....|....|:| .|.:|.|. :|.:..:..:|.       .:.:...|   ..|||..:
 Worm   143 FLLKNETSESKSENVMRQVYRTCEGL-KNEEIFNANMKT-------AFRELFKDIQKIGSWPAAD 199

  Fly   142 FKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELNTPTFG----EESQLPNSFIEIL---- 198
            ..|.:...:|:           |::.|       :|:|.:..||    ..:::|  |:|:.
 Worm   200 KNWDETKLNLN-----------EMLLN-------IVKLGSSNFGLFQIRPTEVP--FLEVAPDMA 244

  Fly   199 ----------SVLY-------------IIKVPSSEIITL------------ARKMR--------- 219
                      .:::             :|.....:.|||            |.|::
 Worm   245 RSPKVSANFQQIIFDILEKNGLQPDENVIADDVEDYITLEETLSQYAYDYNAEKVQFSKLQAQVP 309

  Fly   220 --TLELLLKTMINPIDTLNNRYISIRDFQME-TGHNWQRFFEILIGSSAAPELQVLVRNFRYFTA 281
              .||.:::.|:||    |.:.:.:...:.. ..|....||:..:.
 Worm   310 SLKLEKIIEEMMNP----NRKKLLVTKVKPRMVAHKHSLFFDEKMN------------------- 351

  Fly   282 LKELMDKQDARLVASYIMTRFAIFLLDETMGGRESTECVSQVRRNMNLAANMLYKE--RFFEDST 344
            |::|:.....|.:|:|::    .:.:|..|.|....:.|.:.|....|....|.|.  |.|..:.
 Worm   352 LEKLLKSTPKRTLANYLI----FYYMDHAMNGLSVHDNVIKKRNCEKLVIEYLPKASLRVFVRNH 412

  Fly   345 FSANILEIKDIFEKLRHQFLLQVDQNHLELTALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQY 409
            |....|:|.|...:...:..:::.|....|.|...|..:.|.|.:. .::..||..:.:
 Worm   413 FEKGNLKIVDEMAEETKKSFIEMLQESTWLGADSKKNAILKLEKMG-KMIGYPKEFEKK------ 470

  Fly   410 YQDLQFPTGELDYHQEHLKVLQFRT-QKMLAQSSKGHSEEQNILTYRSQAAPLPP---------- 463
                    |.||...|.||:|...| ..:|.:..:.|.|:.  :.:.:...|:.|
 Worm   471 --------GALDKMFETLKLLPKDTLYGILKKIGRFHMEQG--IEFVALETPMDPVLPVLMTNAF 525

  Fly   464 --------------PQPFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGNDQSFRS--- 511
                          ..|.|..........:|.|.|:||.....|.|.||....:|..:|:..
 Worm   526 YTDRNHLSFLVGYMDDPLFDATYPKYVNIALTGNILAHETSHGFDTAGIKRDENGEVRSWMKPED 590

  Fly   512 -HRFEEAVSCL------------SRN---SENIDESMGDIAGLELAYFTYAKM--AKNRNRLDFT 558
             ..:.:...||            .:|   :..::|.:.|:.|:.:|:..:.|:  :|.:..:.|.
 Worm   591 LKEYGKKTQCLVDQYNEYDDPVFGKNLNGTTTLNEMVADMIGVTVAWKVFEKLDSSKEQKVIGFE 655

  Fly   559 HLPPEQIFFLNVGQFFCG--NSDMLVQ-----YKEDQVRLQRAIEGFEPFDKAFGCYRNKPKHEK 616
            :...::::|......||.  .:..||:     :.....|:.........|..||.|....|.:.|
 Worm   656 NENIDKLYFRAAALDFCSLPPTTSLVEELTRVHPTGNFRVNGIFSNMPQFATAFNCPEGSPMNPK 720

  Fly   617 CR 618
            .|
 Worm   721 TR 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	126/703 (18%)
nep-6	NP_494537.1	M13	105..724	CDD:189000	127/705 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910