Protein Alignment Nepl8 and nep-4

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: NP_509156.2
• Gene: nep-4 / 183746
• WormBaseID: WBGene00016896
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 640
• Identity: 105/640 - (16%)
• Similarity: 183/640 - (28%)
• Gaps: 262/640 - (40%)

  Fly     1 MWIICLL-LVPLVAASSN--TRLLNGILSHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQML 62
            ||:|.|. .:|...|..:  ..:.|.:...||.:::||:::|.|||...::.       |||::
 Worm     1 MWLIILFCFLPTQNAYEHPFDFIENALEKIVDWKSDPCDDFYRHACPVGSIE-------DIIKV- 57

  Fly    63 DHQVNQNLVKLMDELEMS-SQLPDFNVSSVDGKVL-----RYYLSCRGAPRNM----DSLSQYLK 117
                  ::..|.|.|..| .|....|    :|||.     |.::.|....:.:    |...:::.
 Worm    58 ------SMQPLKDALNHSWKQKGQRN----EGKVYNINFRRSHICCHFFCKLLFIYYDYQYRFIN 112

  Fly   118 VISPGEGLTWPQFIPDGSSWPQENFKWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVELN-T 181
            .::..:|:..|.:                                            |.||.| |
 Worm   113 YVTFYDGMLQPLY--------------------------------------------YHVEANVT 133

  Fly   182 PTFGEESQLPNSFIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRDFQ 246
            ....|..|:....:| |..:::.|.|
 Worm   134 DGINEIHQMMEDMVE-LGNIWLEKTP--------------------------------------- 158

  Fly   247 METGHNWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLD--E 309
                  |      :|.::...|::.:....:...:|.:              .|.|...||.  |
 Worm   159 ------W------VINNNLTEEMKNITNAIKMPVSLTK--------------YTNFIYNLLSPIE 197

  Fly   310 TMGGRESTECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLEL 374
            |    :...|||:                 ||.                        :..|.|..
 Worm   198 T----DFLNCVSE-----------------FEG------------------------IQNNTLFC 217

  Fly   375 TALQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQD-----------LQFPTGELDYHQEHLK 428
            .....|.|||..                    |.|:.|           ..||    :|:  |..
 Worm   218 LFYSAKIFVRTR--------------------GSYFIDDNGYNAEGTIYFGFP----NYY--HTT 256

  Fly   429 VLQFRTQKMLAQSSK-GHSEEQNILTYRSQAAPLPPPQPFFQLESEDVFKYSLMGYIMAHHLISA 492
            ...:|..|:....:: ||......:.:...    |...|:|...:||..:...:.....::
 Worm   257 YGNWRASKLGYTGTRVGHEIGHTFIEHSIN----PDGLPYFSKPAEDCVQNQYLKTCNEYY---- 313

  Fly   493 FATEGITIGSDGNDQSFRSHRFEEAVSCLSRNSENIDESMGDIAGLELAYFTYAKMAKN--RNRL 555
               ||                  |.....:.:....|::..|:.||:|||....:...:  |.:.
 Worm   314 ---EG------------------EVPDACNTSDYTFDDNGADVFGLQLAYAILERDLSDQLREQA 357

  Fly   556 DFTHLPPEQIFFLNVGQFFCGNSDMLV---QYKEDQVRLQRAIEGFEPFDKAFGC 607
            |...:..||:.|.:....||..|....   .:....||: .|:.....|.:||.|
 Worm   358 DGLKITNEQLLFYSFAYRFCRGSKSNTTDGSHSHHNVRI-NAVAQMPGFQQAFNC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	96/606 (16%)
nep-4	NP_509156.2	GluZincin	250..425	CDD:387391	37/198 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000