Protein Alignment Nepl8 and LOC1274438

DIOPT Version :10

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_061499078.1
• Gene: LOC1274438 / 1274438
• VectorBaseID: AGAMI1_006356
• Length: 792
• Species: Anopheles gambiae
• Alignment Length: 615
• Identity: 116/615 - (18%)
• Similarity: 229/615 - (37%)
• Gaps: 135/615 - (21%)

  Fly    24 ILSHVDKEANPCENYYNHACGQYNMRHIDDTFFDIIQMLDHQVNQNLVKLMDEL--EMSSQLPDF 86
            |.|.::.:..||..:.|::|                .|::..:  ..||...||  ....||...
Mosquito   212 ISSRMNWDVEPCREFKNYSC----------------SMMESSL--RAVKSAQELADAQMQQLLSL 258

  Fly    87 NVSS--------VDGKVLRYYLSCRGAPRNMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQENFK 143
            |.:|        :.|..||..|:.....|.:|.|..||.:               ||..||....
Mosquito   259 NTTSGIFRKLGRLYGSCLRQELNDTSIRRRLDQLGGYLHI---------------GSVGPQSISP 308

  Fly   144 WLKALAHLHRYGLTNVFFNLE---------VVSNPR---NASEYMVELN---TPTFGEESQLPNS 193
            .:..:..:....|..::::|.         ::..|.   |..|..|..|   .|.:..| ::|:.
Mosquito   309 LVAKIQAIGPLPLIGIYYDLSYGRKPQTLLIIDGPNTPPNILENPVRWNGPRAPPYDVE-EVPDL 372

  Fly   194 FIEILSVLYIIKVPSSEIITLARKMRTLELLLKTMINPIDTLNNRYISIRDF----------QME 248
            ..|:::....:.:.|.:       .::...|:.:.|..::.:...|:. :||          .:.
Mosquito   373 LDELINTFLPLGLSSDQ-------RQSERNLIFSFIRELNQIRRNYVQ-KDFTSSYVLNNVTALS 429

  Fly   249 TGHNWQRFFEILIGSSAAPELQVLVRNFRYFTALKELMDKQDARLVASYIMTRFAIFLLDETMGG 313
            ..|.:..:.|::.|:...|   :::|:..|...|::|:.:...|::.:.::..||:..|..   |
Mosquito   430 NAHPFLIWTELVPGNWTGP---IVIRSPEYLRQLRKLLLQYQNRVIHNALLMLFALNTLPP---G 488

  Fly   314 RES-TECVSQVRRNMNLAANMLYKERFFEDSTFSANILEIKDIFEKLRHQFLLQVDQNHLE-LTA 376
            |.| ..|.......:....:.|:..::.|:....| |...:::||.::         .||: ..:
Mosquito   489 RPSPLVCTRATNWALPEVTSALFVAQYSEEVIRHA-IQRTEEMFENMK---------QHLKRAPS 543

  Fly   377 LQMKFFVRKAEAIEINVVNLPKTDDLRHFIGQYYQDLQFPTGELDYHQEHLKVLQFRTQKMLA-- 439
            |:....||.:: :::.....|...: |..|.....:|:..:.  ::.:..||:.:....:..|
Mosquito   544 LRGAALVRLSQ-LKVQAKVWPTLFN-RTEIASVLDELEISSD--NWFENVLKIYEINNNRTKAVN 604

  Fly   440 ------QSSKGHSEEQNILTYRSQAAPLPPP-----QPFFQLESEDVFKYSLMGYIMAHHLI--- 490
                  |::..:.:...:. |.:.:..:..|     .|:|.........|:.:|..:|..::
Mosquito   605 FTVDSSQTAYAYPQISKVF-YDTLSHSIVVPLSVILVPYFNPVLPPYLHYASLGTTLAKEILRSI 668

  Fly   491 -SAFATEGITIGSDGNDQSFRSHRFEEAVSCLSRNSENIDESMGDIAGLELAYFTYAKMA---KN 551
             .||.|:.:..             ...|||..|..|..  |.:....||::||.|...::   |.
Mosquito   669 TKAFETKIMQC-------------VPGAVSVFSNTSRM--ELLIHSGGLQIAYHTLLSLSGPIKG 718

  Fly   552 RNRLDFTHLPPEQIFFLNVGQFFCGNSDML 581
            .|||....|.|.|||||...|..|..||.:
Mosquito   719 MNRLLGLSLTPPQIFFLISAQQLCAESDYI 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:472708	114/607 (19%)
LOC1274438	XP_061499078.1	None