Protein Alignment Nepl8 and ece2

DIOPT Version :9

• Sequence 1: NP_609795.2
• Gene: Nepl8 / 34983
• FlyBaseID: FBgn0032585
• Length: 619
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 718
• Identity: 155/718 - (21%)
• Similarity: 269/718 - (37%)
• Gaps: 189/718 - (26%)

  Fly    24 ILSHVDKEANPCENYYNHACGQYNMRH-IDD------TFFDIIQMLDHQVNQNLVKLMDELEMSS 81
            ||..:|:..:||:::|.::||.:..|: :.|      ||..|       .:||...|...||.::
 Frog   107 ILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSI-------WDQNQAILKHILENAT 164

  Fly    82 QLPDFNVSS-VDGKVLRYYLSCRGAPR----NMDSLSQYLKVISPGEGLTWPQFIPDGSSWPQEN 141
                ||.|| .:.|..|:||||....|    ....|:..::.|. |..::        .:|..||
 Frog   165 ----FNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKIG-GWNIS--------GNWRGEN 216

  Fly   142 F-KWLKALAHLHRYGLTNVFFNLEVVSNPRNASEYMVE--------------LNTPTFGEESQLP 191
            | ..||.::..:|   ...||::.|.::.::::..:::              ||....|   ::.
 Frog   217 FMSVLKTVSGTYR---ATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANG---KVL 275

  Fly   192 NSFIEILSVLYIIKV-------PSSEIITLARKMRTLELLLKTMINPID------TLNNRYISIR 243
            :::::     |::.|       |.|..:.:.:.:. .|.||..:..|.|      .:.|| ::|.
 Frog   276 DAYLQ-----YMVSVGELLGGSPGSVDMQMTQILE-FETLLANLTVPQDERRDEEKIYNR-MTIS 333

  Fly   244 DFQ-METGHNWQRFFEILIGSSAAPELQ-VLVRNFRYFTALKELMDKQDARLVASYIM------- 299
            :.| :....:|..:....:......:.: |:|....|...:.||::..|..|:.:|::
 Frog   334 ELQSLAPAFDWMDYLTFALSPLDLNDTEPVVVYGKEYLQQVSELVNNTDPMLLNNYLVWNLVQKM 398

  Fly   300 -----TRFAIF---LLDETMGGRES-----TECVSQVRRNMNLAANMLYKERFFEDSTFSAN--- 348
                 :||...   ||:...|.::|     ..|:|.....:..|...|     |..|||..|
 Frog   399 SSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSL-----FVKSTFDKNSKN 458

  Fly   349 -----ILEIKDIFEKLRHQFLLQVDQNHLELTALQ-MKFFVRKAEAIEINVVNLPKTDDLRHFIG 407
                 |.||:|.||              |.|..|. |....|:|..        .|.|.:...||
 Frog   459 IAEQMISEIRDAFE--------------LTLGGLTWMDEKTRRAAK--------EKADAIYDMIG 501

  Fly   408 QYYQDLQFPTGELD------------YHQEHLKVLQFRTQKMLAQSSKGHSEEQNILTYRSQAAP 460
              :.|....|.|||            :.|..|....|..:.|..|..|..:.||..:|.::..|.
 Frog   502 --FPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAY 564

  Fly   461 LPPPQ------------PFFQLESEDVFKYSLMGYIMAHHLISAFATEGITIGSDGN----DQSF 509
            ..|.:            ||:.........:..:|.:|.|.|..||..:|.....|||    .|:.
 Frog   565 YLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNS 629

  Fly   510 RSHRFEEAVSCL-------SRNSENID------ESMGDIAGLELAYFTYAK-MAKN--RNRLDFT 558
            ....|:....|:       :.|.|.::      |::.|..||:.||..|.. :.|:  ..:|...
 Frog   630 SLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGV 694

  Fly   559 HLPPEQIFFLNVGQFFC------GNSDMLV--QYKEDQVRLQRAIEGFEPFDKAFGCYRNKP--- 612
            .|...|:||:...|.:|      .:.:.||  .:...:.|:...:...:.|.:.|.|.:..|
 Frog   695 GLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNP 759

  Fly   613 -KH 614
             ||
 Frog   760 GKH 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl8	NP_609795.2	GluZincin	32..618	CDD:301352	152/710 (21%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	152/710 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010