Protein Alignment dac and dach1

DIOPT Version :10

• Sequence 1: NP_723971.1
• Gene: dac / 34982
• FlyBaseID: FBgn0005677
• Length: 1081
• Species: Drosophila melanogaster
• Sequence 2: NP_001072176.1
• Gene: dach1 / 779442
• XenbaseID: XB-GENE-980849
• Length: 692
• Species: Xenopus tropicalis
• Alignment Length: 829
• Identity: 234/829 - (28%)
• Similarity: 330/829 - (39%)
• Gaps: 292/829 - (35%)

  Fly    72 NSSRGANEDRPNGRSSHTGRGSSCSPASSPSR--------HPSAVSPV--SSLNHSMMQQMQQQQ 126
            :||..::....|..||.|   :|.||:.:||.        .|:|.:||  |||:
 Frog    21 SSSASSSSSSTNSSSSAT---NSPSPSIAPSSSGQSLYRPEPTAATPVTPSSLS----------- 71

  Fly   127 QQQQQQQQQQQHHQLSPPPH--------------GMPSGNGLPTGLPPRMPHGLPPHSLGLLNSL 177
                           ||.|:              |....||:.|..   ....|.| ||...||.
 Frog    72 ---------------SPAPNLTASNSSSQGAAGTGGGGSNGILTNC---SSSSLSP-SLTTTNSS 117

  Fly   178 QMMHH-----------------ASPLELMAAAHHHVPPRS-YNSPPPISTSDPSANECKLVEYRG 224
            ...|:                 :|.....:|...::|.:. |::|.|:. :.|..|||::|:.||
 Frog   118 SSHHNNSIIPSTPATSTSTTSTSSNSSSSSAPTSNLPGKPVYSTPSPVE-NIPQNNECRMVDLRG 181

  Fly   225 QKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQPG 289
            .|||:|.:....::||||||:||||||||||||||||||||:|.|:|||||||||||||||||||
 Frog   182 AKVASFTVDGSELICLPQAFDLFLKHLVGGLHTVYTKLKRLEITPVVCNVEQVRILRGLGAIQPG 246

  Fly   290 VNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLSLPPTHLSQHPQ 354
            ||||||:..|||:.||.|||.|                |||||||||| ...::.|     .:|.
 Frog   247 VNRCKLISRKDFETLYNDCTNA----------------SSRPGRPPKR-TQSVTXP-----DNPH 289

  Fly   355 LKKHRLDNGDYAYENGHISDMKSPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGM-PPHGLH 418
            :..|.:                                         ||   |||||| ||.||.
 Frog   290 IMPHTV-----------------------------------------PG---LMSPGMIPPTGLT 310

  Fly   419 ARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQAMGVGGA 483
            |   :....|||.||.::                                       :||.|...
 Frog   311 A---AAAXAAAATNAAIA---------------------------------------EAMKVKKI 333

  Fly   484 VVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAG--- 545
            .::.:.|.                            .|.|..||     |.|:..|.:|..|
 Frog   334 KLEAMTNY----------------------------HGSNNQHG-----ADSDNGDLNSSVGLEL 365

  Fly   546 -------------SPARGGSRSLDEGSRSGVGGGVA---------SHVGGGII--GVEDDEEEEE 586
                         .|....:.::.:.:.......:|         |.|...:|  .|.|......
 Frog   366 PFMMMPHPLIPVSLPPASVTMAMSQMNHLSTIANMAAAAQVHSTPSRVETSVIKERVPDSPSPAP 430

  Fly   587 NLSDENQSEVDERCLAKDDEDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSH 651
            :|.|..:             .:|.......|:.|::.|...:::....:||:..|.:...:|||.
 Frog   431 SLEDGRR-------------PVSHPSSHRSSSVSSSPARTESSSDRIPVHQNGISINQMLMGLSP 482

  Fly   652 LGVVPPHQRGSPSSAEAAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNE 716
             .::|..:.|..:..|....|.:.....:.:.|:.                  ||...
 Frog   483 -NIIPGPKEGDLAGHEVGHEAKRMHMEKDETPLST------------------PTARD------- 521

  Fly   717 ALLAANDAAALAG-GLALGPLGIDAHAAVP--ASSTETLLRNIQSLLKVAADNARQQERQISYEK 778
                :.|..:|:| |..|.| |..:....|  .||.||||.|||.|||||.||||.||:|:..||
 Frog   522 ----SFDKLSLSGHGQHLPP-GYPSPFLFPDGLSSIETLLTNIQGLLKVAIDNARAQEKQVQMEK 581

  Fly   779 AELKMDVLREREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQL 827
            .||||::.||||::::||:||..|:|.|.:.|||.::|:|.:.:.|:.|
 Frog   582 TELKMELFRERELRETLEKQLAVEQKNRAIIQKRLKKEKKAKRKLQEAL 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dac	NP_723971.1	DHD_Dac	215..309	CDD:410784	69/93 (74%)
dach1	NP_001072176.1	DHD_Dac	172..266	CDD:410784	69/93 (74%)