DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment dac and Dach2

DIOPT Version :9

Sequence 1:	NP_723971.1	Gene:	dac / 34982	FlyBaseID:	FBgn0005677	Length:	1081	Species:	Drosophila melanogaster
Sequence 2:	XP_017457838.2	Gene:	Dach2 / 302333	RGDID:	1561687	Length:	433	Species:	Rattus norvegicus

Alignment Length:	495	Identity:	114/495 - (23%)
Similarity:	168/495 - (33%)	Gaps:	204/495 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   375 MKSPLLANG---------------------YNPPPINH-------MAFMQMNAHHPGAAALMSPG 411
            ::|||.|.|                     .||...||       :.||.|  .||    |:...
  Rat    50 IQSPLAAPGAQHGIAHAALAGQPGLGGAPTLNPLQQNHLLSNRLDLPFMMM--PHP----LLPVS 108

  Fly   412 MPPHGLHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQ 476
            :||..: |...:||      |...:.|||.|.|:.               |
  Rat   109 LPPASV-AMAMNQM------NHLNTIANMAAAAQI---------------H-------------- 137

  Fly   477 AMGVGGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKS---GGNTDHGGSNCDAGSERS 538
                  :.:.|.|..::.|..|.       ||   ||..:|.:|   |..|....|:
  Rat   138 ------SPLSRAGASVIKERIPE-------SP---SPAPSLEESHRPGSQTSSHPSS-------- 178

  Fly   539 DCHSVAGSPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAK 603
               ||:.||::                             .|.:.|...:...|:.|:   .:.:
  Rat   179 ---SVSSSPSQ-----------------------------MDHQSERMVMMPNNREEI---IIDQ 208

  Fly   604 DD-EDLSDTERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAE 667
            |: :.:...:|||...               ||.|    ||.....|..:.:.|..::......|
  Rat   209 DNGQSIKKFQRDNKDI---------------QLSQ----HHLLNTFLHWIELAPLSKKSLLHQKE 254

  Fly   668 AAAAALQHQRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLA 732
            ..|.....:..|:..|||...|:              |.|..|.....::|
  Rat   255 VPAQIPMMKSPLDKIQLAPGQAL--------------PPGFPGPFIFADSL-------------- 291

  Fly   733 LGPLGIDAHAAVPASSTETLLRNIQ----------SLLKVAADNARQQERQISYEKAELKMDVLR 787
                          ||.||||.|||          .|||||.||||.||:||..||.||::::.|
  Rat   292 --------------SSVETLLTNIQVNNISINKINGLLKVALDNARIQEKQIQQEKKELRIELYR 342

  Fly   788 EREVKDSLERQLVDERKLRVLYQKRFRRERKIRIRYQQQL 827
            |||::::|||||..|.:.|...|||.::|:|.:.:.|:.|
  Rat   343 EREIRENLERQLAVELQSRSTMQKRLKKEKKAKRKLQEAL 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
dac	NP_723971.1	Ski_Sno	209..310	CDD:280577
Dach2	XP_017457838.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206899at33208
OrthoFinder	1	1.000	-	-		FOG0002588
OrthoInspector	1	1.000	-	-		otm46043
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1700
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.010