Protein Alignment dac and dachb

DIOPT Version :9

• Sequence 1: NP_723971.1
• Gene: dac / 34982
• FlyBaseID: FBgn0005677
• Length: 1081
• Species: Drosophila melanogaster
• Sequence 2: NP_694488.2
• Gene: dachb / 192122
• ZFINID: ZDB-GENE-020402-4
• Length: 567
• Species: Danio rerio
• Alignment Length: 737
• Identity: 205/737 - (27%)
• Similarity: 270/737 - (36%)
• Gaps: 305/737 - (41%)

  Fly   162 MPHGLPPHSLGLLNSLQMMH----HASPLELMAAAHHHVPPRSYNSPPPISTSDPSANECKLVEY 222
            :|..||.||.....|.::..    .:||.|         .||..||.|    |..:.||||:||.
Zfish     6 VPATLPVHSGTSAVSGKLFRTEPFFSSPAE---------APRIINSLP----SGGTTNECKIVEV 57

  Fly   223 RGQKVAAFIISNETMLCLPQAFELFLKHLVGGLHTVYTKLKRLDIVPLVCNVEQVRILRGLGAIQ 287
            .|.|||:|.:..:.::||||.|:||||||||||||||||||||||.|:||.|||||:||||||||
Zfish    58 HGVKVASFSVDGQELICLPQVFDLFLKHLVGGLHTVYTKLKRLDINPVVCTVEQVRVLRGLGAIQ 122

  Fly   288 PGVNRCKLLCCKDFDILYRDCTTARCLSIKPPESNSLQFRSSRPGRPPKRGPVGLS--------- 343
            ||||||||:..|||:.||.|||.|                ||||||||||. .|.|
Zfish   123 PGVNRCKLISRKDFEALYNDCTNA----------------SSRPGRPPKRS-YGASVQESPRILH 170

  Fly   344 ----------LPPTHLS------------QHPQLKKHRLDNG----------------------- 363
                      |.||.|:            ....:..|:..||
Zfish   171 HRANLLSPALLSPTGLTTAAMAEALKIQKMKMMMNLHKTHNGSEFDSDELNSNAGTVCSTLSWER 235

  Fly   364 -----------DYAYENGHISDMK-SPLLANGYNPPPINHMAFMQMNAHHPGAAALMSPGMPPHG 416
                       .::..|..::.:: :.||||....|      ||.|  .||    |:..|:||..
Zfish   236 EKHSSPASEKTQHSLNNSQLNSLQHTHLLANRLELP------FMMM--PHP----LLPVGLPPAS 288

  Fly   417 LHARPESQMLKAAAQNAGMSAANMDALARSGIWENCRAAYEDIVKHLERLREERTDERQQ-AMGV 480
            : |...:||      |...:.|||.|.|:         .:..:.:....:::||.:|... ...|
Zfish   289 V-AMAMNQM------NHLNTIANMVASAQ---------VHSPVSRPTSAIKQERFEESPSLTPSV 337

  Fly   481 GGAVVDRVGNVMVAEHKPRDLSSRNCSPTRQSPVLNLSKSGGNTDHGGSNCDAGSERSDCHSVAG 545
            .|.|..:      .|..|:..||...|||                               |....
Zfish   338 EGIVSQK------TEPSPQQSSSVPSSPT-------------------------------HPYTH 365

  Fly   546 SPARGGSRSLDEGSRSGVGGGVASHVGGGIIGVEDDEEEEENLSDENQSEVDERCLAKDDEDLSD 610
            ||.:....:.||                                   |.|.|.
Zfish   366 SPLKTAYDAHDE-----------------------------------QRETDS------------ 383

  Fly   611 TERDNLSTGSAAAAAAAAAAAAHQLHQHAASHHHQTVGLSHLGVVPPHQRGSPSSAEAAAAALQH 675
                                                                             
Zfish   384 ----------------------------------------------------------------- 383

  Fly   676 QRALNYSQLAAAAAVANGAAVGGGAVANGPTGGGGALTPNEALLAANDAAALAGGLALGPLGIDA 740
              ||:.::|:......|                  |:.|  ||.....|.....|.....|..|.
Zfish   384 --ALHVNRLSNDRVEQN------------------AVKP--ALFEKVPAQTFPSGFPASLLFTDG 426

  Fly   741 HAAVPASSTETLLRNIQSLLKVAADNARQQERQISYEKAELKMDVLREREVKDSLERQLVDERKL 805
                 .||.||||.|:|.|||||.:|||.||:|:..|:.||||::.||||:::||||||..|.:.
Zfish   427 -----LSSVETLLTNVQGLLKVALENARLQEKQLQQERRELKMELYREREMRESLERQLTSELRT 486

  Fly   806 RVLYQKRFRRERKIRIRYQQQL 827
            |...|:|.::|:|.:.|.|:.|
Zfish   487 RATIQRRLKKEKKAKRRLQEAL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dac	NP_723971.1	Ski_Sno	209..310	CDD:280577	70/100 (70%)
dachb	NP_694488.2	Ski_Sno	48..145	CDD:280577	69/96 (72%)
		DUF4200	437..524	CDD:290574	36/72 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594419
Domainoid	1	1.000	162	1.000	Domainoid score	I3949
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2929
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206899at33208
OrthoFinder	1	1.000	-	-		FOG0002588
OrthoInspector	1	1.000	-	-		otm24380
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12577
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4062
SonicParanoid	1	1.000	-	-		X1700
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	11.080