DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and Cht4

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	123/449 - (27%)
Similarity:	205/449 - (45%)	Gaps:	94/449 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SLWLSLALSLAVLAQFKVSAAPNLV-CFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVN 67
            |:|...||.|. |.|  |:::..|: |::.:..:.|.|..:|:..||:.:|  |||:.|.:.|:
  Fly     5 SIWALAALCLC-LGQ--VASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSL--CTHISYTFFGI- 63

  Fly    68 ADNYEMQSINKRLDLEQ--RHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHR 130
            :|..|.:|::..||::.  ..::|..::|:|.|::|.|..|||   ..||:.....:.:......
  Fly    64 SDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGG---WNEGSTKYSAMAADPAKRA 125

  Fly   131 RFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVT 195
            .|:.::...:::|:||||||..:.|        |..|.                  ||..:....
  Fly   126 TFVSTSLAFIQQYSFDGLDLDWEYP--------GQRGG------------------SEADRENFV 164

  Fly   196 ALIKDLSAALKQNDLLLSLTV-LPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEADFSA 259
            .|::::.....|..|.|.:.| ....::|..||.|:|:..|.|||:.|:||
  Fly   165 TLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDF-------------- 215

  Fly   260 PTYEAVGQNRLGHYNLNF-------QMEHWLLQRVPANKINIGIATYGRSWKMSKDSGD-SGMPV 316
              :.|:.    |:..||.       .:::||....||.|:.:||..||.|::||..|.: .|...
  Fly   216 --HMALD----GYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAAC 274

  Fly   317 VPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADEN 381
            :    ||..||..:::.|.|.:.|||  :.|......:...||             |||:
  Fly   275 I----GPGTAGVYTRENGFLGYHEIC--LNNWQTVFDQENGAP-------------YAFQ----- 315

  Fly   382 GDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAIKYRL 440
            ||.  ||.||:|:|...|.....:|||||..::.:..|||||.| .:.:|:|:.:...|
  Fly   316 GDQ--WIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLC-GESYPLLKTMNRAL 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	114/425 (27%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	106/403 (26%)
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	113/423 (27%)
		Glyco_18	28..351	CDD:214753	105/400 (26%)
		CBM_14	421..462	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840