DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and Cht5

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster

Alignment Length:	437	Identity:	103/437 - (23%)
Similarity:	185/437 - (42%)	Gaps:	81/437 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LSLAVLAQFKVSA-----APNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADN 70
            |.|.||..:..:.     |..:||::.:....|.|:.::.:.|:...|  |||::|.:.|||..:
  Fly     8 LLLGVLCSWPAATVASDQASRIVCYFSNWAVYRTGIGRYGLEDVPADL--CTHIIYSFIGVNDKS 70

  Fly    71 YEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIES 135
            :::..|:..||::|...::.|.:|:..|::|..::|||.|:  .|::|.::: :.:...:.||.|
  Fly    71 WDVLVIDPELDVDQGGFSKFTQLKKSNPNVKLEIAVGGWAE--GGSKYSQMV-AVRDRRQSFIRS 132

  Fly   136 ARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKD 200
            ....:::|||||.||..:.|....|  .|:.|...|..  :|..:.....:.|....::|..:..
  Fly   133 VVRFMKQYNFDGFDLDWEYPGATDR--GGNYGDKDKFL--YFVEELRRAFDREGRGWEITMAVPV 193

  Fly   201 LSAALKQNDLLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFD-------FLTPQRNPEEADFS 258
            ....|.:.                 |..|.:..:||.|:..|:|       |         ||..
  Fly   194 AKFRLNEG-----------------YHVPELCEALDAIHAMTYDLRGNWAGF---------ADVH 232

  Fly   259 APTYEAV-GQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPSTQ- 321
            :|.|:.. .|......|:|..:..|.....||||:.:|:..|||::.:|..:.:..|....:.:
  Fly   233 SPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMGTYINKEA 297

  Fly   322 -GPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRY-------GSYAFRAA 378
             |.|| ||.:...|.|.:.|||:                  .|:|.:|.:       |...:...
  Fly   298 GGGAP-GPYTNASGFLAYYEICT------------------EVMDKSKGWTVEWDDAGMVPYTYK 343

  Fly   379 DENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQC 425
            |..     |:.|::..|...|..:.:.|...|...:.:..|||.|.|
  Fly   344 DTQ-----WVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMC 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	98/417 (24%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	93/408 (23%)
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	93/409 (23%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	98/416 (24%)
		Trypan_PARP	367..469	CDD:114603	6/19 (32%)
		CBM_14	531..578	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910