DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and chia.2

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	448	Identity:	114/448 - (25%)
Similarity:	193/448 - (43%)	Gaps:	88/448 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 GSLWLSLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVN 67
            |.|.|...|.| ||.....|.  .:.|::.:....|.|:.:::..:::..|  ||||.|.:|.:|
Zfish     2 GRLTLVAGLGL-VLCHLAFSM--EMGCYFTNWSQYRPGIGKYTPANVDPFL--CTHLFYAFAMIN 61

  Fly    68 ADN----YEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQG 128
            ..|    ||..        ::........:|...||::.||:|||   ...|:....::.|....
Zfish    62 HANELITYEWN--------DETLYKAFNELKNTNPHLRTLLAVGG---WNFGSTQFSIMVSSAAN 115

  Fly   129 HRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQ 193
            .:.||:|:...:|.|.|||:||..:.|        |..||..:..::|
Zfish   116 RQTFIQSSIKFLRTYGFDGMDLDWEYP--------GSRGSPPEDKQRF----------------- 155

  Fly   194 VTALIKDLSAALK-------QNDLLLSLTVLP---NVNSSWYYDAPSIAPSLDFINLGTFDFL-T 247
             |.|.|:|..|.:       :..|:||..|..   .::..  |:...||..|||||:.|:||. |
Zfish   156 -TLLCKELLEAYEAEGKATGRRRLMLSAAVSAGKGTIDDG--YEIAEIAKYLDFINIMTYDFHGT 217

  Fly   248 PQRNPEEADFSAPTYE-AVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGD 311
            .:|   ....::|.|: :..:..|.::|.::.|.:|.....|..|:.:|.|||||:::::.....
Zfish   218 WER---FTGHNSPLYQGSKDEGDLVYFNTDYAMRYWRDNGTPVEKLRMGFATYGRTFRLTSSDTS 279

  Fly   312 SGMPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFR 376
            .|.|    ..|||.||..:::.|..::.|||..:...:          |:.:.|....|
Zfish   280 VGAP----ASGPASAGTYTREAGFWSYYEICGFLEGTT----------VQWIDDQKVPY------ 324

  Fly   377 AADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQ-CTNDRFPML 433
             |.:|.:   |:.:|..:|..:|..|.:.:..||..::.|..|||.|| |.....|::
Zfish   325 -ATKNSE---WVGFDTKESYETKVRYLKDKKFGGAFVWALDLDDFAGQFCGQGNHPLM 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	106/425 (25%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	99/407 (24%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	106/424 (25%)
		Glyco_18	24..363	CDD:214753	99/406 (24%)
		CBM_14	423..468	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592074
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950