DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and Idgf6

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	445	Identity:	227/445 - (51%)
Similarity:	318/445 - (71%)	Gaps:	16/445 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LALSLAVLAQFKVSA----APNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNAD 69
            ::|.||.:...||.|    ..:|||:|||....::||.:..:.::|.|||||.:|||||||:..|
  Fly     9 VSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIERD 73

  Fly    70 NYEMQSINKRLDLE--QRHLAQITSMKERYPHIKFLLSVGGDADTYEG-------NQYIKLLESG 125
            :::..|:|::|||:  :.....:|.:|.:||::|.|||||||.|....       |:|::||||
  Fly    74 SHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLES- 137

  Fly   126 QQGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETH 190
            ..|..||:.:...||:.|.|||||:|.|.|:|||:|||..:||.||.|||.|:||.|||.:||.|
  Fly   138 PTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEEH 202

  Fly   191 KGQVTALIKDLSAALKQNDLLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEA 255
            |.|.|||::|:..|.:.::||||.|||||||||.:||.|::...|||:|||||||.|||||||.|
  Fly   203 KEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEVA 267

  Fly   256 DFSAPTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPST 320
            |::||.||...:|  ..:|:..|:::||....||:|||:|:|||||.||::.||||:|:|.|...
  Fly   268 DYAAPIYELSERN--PEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVKDV 330

  Fly   321 QGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHG 385
            :..||.|..::..|:.:|.|:|:|:||.:|:..:|.|||:.:|.||.||:||||:||||:.||:|
  Fly   331 KDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGDNG 395

  Fly   386 LWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAIKYRL 440
            :|:|::|||:|:.||.|.|..||||||||||:.|||||.|||:::|:||||||||
  Fly   396 IWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYRL 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	219/422 (52%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	204/400 (51%)
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	219/422 (52%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	204/400 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850