DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and chia.4

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_956740.1	Gene:	chia.4 / 337333	ZFINID:	ZDB-GENE-030131-9279	Length:	475	Species:	Danio rerio

Alignment Length:	456	Identity:	123/456 - (26%)
Similarity:	202/456 - (44%)	Gaps:	101/456 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MTGSLWLSLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQF--SMIDIELALQFCTHLVYGY 63
            |||.::|: .:|||:.   :...|..|.|::.:....|..:.::  |.:|..|    ||||:|.:
Zfish     1 MTGLIFLA-GISLALC---QCGLASQLACYFANWSQYRPDVGKYMPSNVDPHL----CTHLIYAF 57

  Fly    64 AGVNADNYEMQSINKRLDLEQRHLAQ-ITSMKERYPHIKFLLSVGGDADTYE-GNQYIKLLESGQ 126
            :.:|..|....|     :.....|.| ..::|:..|::|.||:||    |.. |:.....:.|..
Zfish    58 SVINIKNKLATS-----EWNDETLYQSFNALKQSNPNLKTLLAVG----TLNLGSTQFSRMVSTP 113

  Fly   127 QGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETH- 190
            |..:.||||:...:|.:.||||||..:.|           ||.                ||...
Zfish   114 QKRQTFIESSIKFLRTHGFDGLDLDWEYP-----------GSG----------------ESPPED 151

  Fly   191 KGQVTALIKDL-------SAALKQNDLLLSLTVLPN---VNSSWYYDAPSIAPSLDFINLGTFDF 245
            |.:.|.|.|:|       |.|.::..|:|:..|...   :::.  |:...::..|||||:.|:||
Zfish   152 KHRFTLLCKELLKAYQAESKATRRPRLMLTAAVAARKGIIDAG--YEIAEVSKYLDFINIMTYDF 214

  Fly   246 ------LTPQRNPEEADFSAPTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWK 304
                  :|...:|...| |..|.:.:      :||.:|.|.:|..|..|..|:.:|.|.|||::.
Zfish   215 HGSWENVTGHNSPLYRD-SRDTGDQI------YYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFC 272

  Fly   305 MSKDSGDSGMPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKR 369
            :|......|.||    .|||.||..:::.|..::.|||:.:          ..|.|:::.|....
Zfish   273 LSSAVNGLGAPV----SGPASAGTYTREAGYWSYYEICTFL----------QRASVEQIADQKVP 323

  Fly   370 YGSYAFRAADENGDHGL-WISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQ-CTNDRFPM 432
            |.:           .|| |:.:||..|..:|..|.:.:..||..::.|..|||.|| |...::|:
Zfish   324 YAT-----------EGLNWVGFDDQKSYETKVDYLKEKGFGGAFVWSLDLDDFSGQFCGQGKYPL 377

  Fly   433 L 433
            :
Zfish   378 I 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	115/431 (27%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	108/413 (26%)
chia.4	NP_956740.1	Glyco_18	22..363	CDD:214753	108/414 (26%)
		GH18_chitolectin_chitotriosidase	25..381	CDD:119351	114/428 (27%)
		ChtBD2	425..473	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592068
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.950