DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf3 and Idgf4

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	438	Identity:	215/438 - (49%)
Similarity:	310/438 - (70%)	Gaps:	8/438 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLALSLAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNYE 72
            ||.:....:.|...:.:.:|:|:||.....|:||::..:.|:|.|||:||||||||||:|..:.:
  Fly     8 SLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNK 72

  Fly    73 MQSINKRLDLE--QRHLAQITSMKERYPHIKFLLSVGGDADTY--EGNQYIKLLESGQQGHRRFI 133
            :.|.|::|||:  .....|:|.:|.:||.:|.|||||||.||.  |.|:|:.|||| ......||
  Fly    73 LVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLES-SNARIPFI 136

  Fly   134 ESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALI 198
            .||..||:.|.||||||..|.|:|||:||||.:|..||.|||.|:||.:||.::|.||...|||:
  Fly   137 NSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALV 201

  Fly   199 KDLSAALKQNDLLLSLTVLPNVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEADFSAPTYE 263
            ::|..|.:.:..:|.|:||||||||.::|.|:|..:||::||.|:||.||:||.|.|||.||.||
  Fly   202 RELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAPIYE 266

  Fly   264 AVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPSTQGPAPAGP 328
            .  ..|...:|:|:|:::|...|.||.|||:|||||||:||::||||.:|:|.|....|.||||.
  Fly   267 L--NERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGVAPAGT 329

  Fly   329 QSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHGLWISYDDP 393
            |::..|||:|.|:|:.:|||:|.:.:|.:.|:::|.|||||:||||:|:||::|::|:|:.|:||
  Fly   330 QTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDP 394

  Fly   394 DSASSKAMYARARNLGGVALFDLTQDDFRGQCT-NDRFPMLRAIKYRL 440
            |:|:.||.|.:...|||:|:.||:.|||||.|| :|:||:||.:|.:|
  Fly   395 DTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	211/418 (50%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	198/395 (50%)
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	211/418 (50%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	198/395 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469718
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850