DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and Chit1

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_001073157.1	Gene:	Chit1 / 289032	RGDID:	1305646	Length:	464	Species:	Rattus norvegicus

Alignment Length:	447	Identity:	128/447 - (28%)
Similarity:	221/447 - (49%)	Gaps:	81/447 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLALS-LAVLAQFKVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAGVNADNY 71
            ||||: :..|...:..:|..|.|::.:....|.|.|:|...|::..|  |||::|.:||:|  |:
  Rat     4 SLALAGVTTLLMIQWGSAAKLFCYFTNWAQYRSGAARFLPRDVDPNL--CTHVIYAFAGLN--NH 64

  Fly    72 EMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIESA 136
            ::.::...   ::....::.|:|:|.|.:|.||:|||.:   .|.|....:.:.....:.|:.||
  Rat    65 QVSTVEPN---DELFYQELNSLKKRNPKLKTLLAVGGWS---FGTQKFTDMVATASTRQTFVNSA 123

  Fly   137 RDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKDL 201
            ...:|.:.||||||..:.|.::                    |...||.|      :.||||:||
  Rat   124 LSFLRTHGFDGLDLDWEYPGSR--------------------GSPAVDKE------RFTALIQDL 162

  Fly   202 SAALKQ-------NDLLLSLTVLP----NVNSSWYYDAPSIAPSLDFINLGTFDFLTPQRNPEEA 255
            :.|.::       :.|||:..| |    :|::.  |:...|..|||||||..:||.:..  .:..
  Rat   163 AKAFQEEARASGKSRLLLTAAV-PTGRGHVDAG--YEVDKIVQSLDFINLMAYDFHSSW--DKTT 222

  Fly   256 DFSAPTYEAVGQ-NRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPS 319
            ..::|.|:..|: .:....|::..:..||.:..||:|:.:|:..||||:.:: .|.|||:. .|:
  Rat   223 GHNSPLYKRQGETGKDAEKNVDAAVTLWLQKGTPASKLMLGMPAYGRSFTLA-SSSDSGVG-APA 285

  Fly   320 TQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDH 384
            | ||...||.:|::|:|.:.|:||.         :|.    :|:.|....|.|        .|:.
  Rat   286 T-GPGAPGPYTKEKGILVYFEVCSW---------KGK----QRIEDQKVPYVS--------QGNQ 328

  Fly   385 GLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQ-CTNDRFPMLRAIKYRL 440
              |:.:||.:|..:||.|.:.:.|||..::.|..|||:|. |...::|::|.:...|
  Rat   329 --WVGFDDRESFRAKAAYVKQKGLGGAMVWILDGDDFKGSFCNEGQYPLIRTLHQEL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	121/426 (28%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	114/403 (28%)
Chit1	NP_001073157.1	GH18_chitolectin_chitotriosidase	24..383	CDD:119351	121/425 (28%)
Chit1	NP_001073157.1	ChtBD2	416..463	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350395
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950