DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and Cht12

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	424	Identity:	104/424 - (24%)
Similarity:	180/424 - (42%)	Gaps:	89/424 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 NLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYA-GVNADNYEMQSINKRLDLEQRHLAQ 89
            |:.|.||......:|.:||  .:..|..:.|||||.|.. ||:.|:.|::..:|.|.||:..|:.
  Fly    24 NVFCQYDLGSYYYKGRSQF--FEWHLDSRLCTHLVLGSGIGVDGDSGELRITDKILLLEKDKLSS 86

  Fly    90 ITSMKERYPHI-KFLLSVGGDADTYEGNQYIKLLESGQQGHRRFIESARDLVRRYNFDGLDLALQ 153
            :.:||  :..| |.:.::||..:  :.:.:.:::.|.:: ...|..|..:.:.|:.|||:.:..:
  Fly    87 VKTMK--WDSIKKVMFTIGGWEE--DSSSFSRMVASPKK-RDNFYSSMLEFMFRWGFDGVQIDWR 146

  Fly   154 LPRNKPRKVHGDVGSAWKSFKKFFTGDFIVDTESETHKGQVTALIKDLSAALKQNDLLLSLTVLP 218
            .|.                    ..|....|.::      ...|:::|....::|.|:|.:.||.
  Fly   147 YPT--------------------LLGGHPDDRQN------FVILLEELGLIFRKNQLILMVAVLG 185

  Fly   219 NVNSSWY--YDAPSIAPSLDFINLGTFDFLTPQRNPE--EADFSAPT--YEAVGQNRLGHYNLNF 277
            ..::...  |:.|.|....|||:|...|    :::|.  ...::||.  ||.         ::..
  Fly   186 RRDNRILESYNIPEIVNHSDFIHLMMHD----EQDPYHLRLAYNAPLVGYEG---------SVTD 237

  Fly   278 QMEHWLLQRVPANKINIGIATYGRSWKMSKDSGDSGMPVVPSTQGPAPAGP-----QSKQEGLLN 337
            .:.||........|:.:||..:.||:.|.::.         ||.|.|..||     ||.:.|.:.
  Fly   238 SIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQ---------STVGSACKGPGRQTKQSHRPGFMT 293

  Fly   338 WAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRAADENGDHGLWISYDDPDSASSKAMY 402
            :.|.|......|            |:.|...:. .||.|     ||.  |:||::|.|..:|...
  Fly   294 YNEWCVQQSKWS------------RMFDQLAKV-PYATR-----GDQ--WVSYENPRSIWAKMHL 338

  Fly   403 ARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAI 436
            .:...|||...:.:..|||||:| .::..:||.|
  Fly   339 LQEHKLGGAMAWTIDVDDFRGRC-GEQHGLLRVI 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	104/424 (25%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	94/404 (23%)
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	103/423 (24%)
		Glyco_hydro_18	47..355	CDD:279094	88/380 (23%)
		ChtBD2	394..438	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840