DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf3 and cht-2

DIOPT Version :9

Sequence 1:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster
Sequence 2:	NP_495798.2	Gene:	cht-2 / 174363	WormBaseID:	WBGene00011757	Length:	626	Species:	Caenorhabditis elegans

Alignment Length:	396	Identity:	87/396 - (21%)
Similarity:	148/396 - (37%)	Gaps:	91/396 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 THLVYGYAGVNADNYEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKL 121
            ||||:.:..|::|.    |:....|..:..|..:..:..|:|.:|.|.:|||    :|.:||..:
Worm    55 THLVFAFFVVDSDG----SVKLEGDAAKARLEHVKEVASRHPDLKLLYAVGG----WENSQYFSV 111

  Fly   122 LESGQQGHRRFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSAWKSFKKFFTG------D 180
            |.:........|.:...:::.|.|||:|:..:.|      |.|.......:.::.:..      :
Worm   112 LTADHSRRSILISNFVKVIKEYGFDGVDIDWEYP------VTGGAVEGTPADRRNYVNLMRELRN 170

  Fly   181 FIVDTESETHKGQVTALIKDLSAALKQNDLLLSLTVLPNVNSSWY----YDAPSIAPSLDFINLG 241
            .:.|.||||.|   :.||....||                 ..|.    ||...:....||:|:.
Worm   171 ELRDLESETGK---SYLISFAGAA-----------------GHWVLKPGYDLQQLMKYCDFVNVM 215

  Fly   242 TFDFLTPQRNPEEADFS--APTYEAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWK 304
            ::|:.....:...|...  ||...|:.:...|..|::..|:.:..|....:|||:|:..|||.|
Worm   216 SYDYFGAWASKWGAYTGPPAPLQFAMPKKFSGRMNVHATMKDYSCQIKATDKINMGVPFYGRFW- 279

  Fly   305 MSKDSGDSGMPVVPSTQGPAPAGPQSKQEGL------LNWAEICSLMPNPSNSNARGPNAPVKRV 363
              |:.||:    |.||.........:..||.      :.|.::.............|...|.
Worm   280 --KNVGDA----VDSTDDMWRTATATNSEGTKFEGGDVQWRDLHEKFDTTKTKFHSGSKTPF--- 335

  Fly   364 VDPTKRYGSYAFRAADENGDHGLWIS-------YDDPDSASSKAMYARARNLGGVALFDLTQDDF 421
                                  :|:|       |::.:|...|..|....|:|||.::.:..||.
Worm   336 ----------------------IWLSEQKTFVGYENAESLKHKVDYIVENNIGGVMIWAIDFDDD 378

  Fly   422 RGQCTN 427
            :|...|
Worm   379 QGTLLN 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	87/396 (22%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	83/386 (22%)
cht-2	NP_495798.2	Glyco_18	33..376	CDD:214753	83/386 (22%)
		GH18_chitinase-like	35..376	CDD:299167	83/386 (22%)
		ChtBD1_GH18_2	418..469	CDD:211315
		ChtBD1_GH18_2	496..547	CDD:211315
		ChtBD1_GH18_2	567..618	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.770