Protein Alignment CG5888 and Lgr6

DIOPT Version :10

• Sequence 1: NP_609794.1
• Gene: CG5888 / 34980
• FlyBaseID: FBgn0028523
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_001405234.1
• Gene: Lgr6 / 329252
• MGIID: 2441805
• Length: 1004
• Species: Mus musculus
• Alignment Length: 200
• Identity: 53/200 - (26%)
• Similarity: 89/200 - (44%)
• Gaps: 31/200 - (15%)

  Fly   155 STLPENFLENLPALQQLSLKGSSDLPGNILHPLKNLTHLEIVVKNLGKVSGAIFAKQSKLKHLMI 219
            |.:|.: |:.|.|...||:...::|...:.|.|:.|..|.:...:|..:.|..|:....||.||:
Mouse    58 SVVPAD-LDPLTAYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSHIPGQAFSGLHSLKILML 121

  Fly   220 DCDAKNSSVEMSAFGPQELWHMTELQSIEL-FNCGDNVPTELF---------WMSEQ-LAYIGIR 273
                  .|.::.....:.||.:..|||:.| .|....||...|         |:.:. |..|.:|
Mouse   122 ------QSNQLRGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIPVR 180

  Fly   274 --SNISYLSKDFLKVQKKLLTLRLERNNIARLPDQLFRNTPLILEIHLAFNNLDRIQSGLFDKLK 336
              :|:..|         :.:||.|  |:|..:||..|:|...::.:||..|.:..:.:..|:.|.
Mouse   181 ALNNLPAL---------QAMTLAL--NHIRHIPDYAFQNLTSLVVLHLHNNRIQHVGTHSFEGLH 234

  Fly   337 NLQVL 341
            ||:.|
Mouse   235 NLETL 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5888	NP_609794.1	LRR	<160..>359	CDD:443914	50/194 (26%)
		leucine-rich repeat	168..189	CDD:275380	5/20 (25%)
		leucine-rich repeat	190..213	CDD:275380	5/22 (23%)
		leucine-rich repeat	214..243	CDD:275380	7/28 (25%)
		leucine-rich repeat	244..266	CDD:275380	9/31 (29%)
		leucine-rich repeat	267..289	CDD:275380	5/23 (22%)
		leucine-rich repeat	290..313	CDD:275380	9/22 (41%)
		leucine-rich repeat	314..337	CDD:275380	5/22 (23%)
		leucine-rich repeat	338..357	CDD:275380	1/3 (33%)
Lgr6	NP_001405234.1	LRR	<51..350	CDD:443914	52/199 (26%)
		leucine-rich repeat	70..91	CDD:275380	5/20 (25%)
		leucine-rich repeat	92..115	CDD:275380	5/22 (23%)
		leucine-rich repeat	116..139	CDD:275380	7/28 (25%)
		leucine-rich repeat	140..163	CDD:275380	8/22 (36%)
		leucine-rich repeat	164..187	CDD:275380	5/22 (23%)
		leucine-rich repeat	188..211	CDD:275380	10/33 (30%)
		leucine-rich repeat	212..235	CDD:275380	5/22 (23%)
		leucine-rich repeat	236..295	CDD:275380	1/3 (33%)
		LRR	277..>508	CDD:443914
		leucine-rich repeat	296..319	CDD:275380
		leucine-rich repeat	320..341	CDD:275380
		leucine-rich repeat	344..385	CDD:275380
		leucine-rich repeat	391..412	CDD:275380
		leucine-rich repeat	413..436	CDD:275380
		leucine-rich repeat	437..458	CDD:275380
		leucine-rich repeat	461..481	CDD:275380
		7tmA_LGR6	599..875	CDD:320484
		TM helix 1	600..626	CDD:320484
		TM helix 2	634..659	CDD:320484
		TM helix 3	679..709	CDD:320484
		TM helix 4	721..743	CDD:320484
		TM helix 5	765..794	CDD:320484
		TM helix 6	803..833	CDD:320484
		TM helix 7	843..868	CDD:320484