DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and chia.3

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_998378.1	Gene:	chia.3 / 406819	ZFINID:	ZDB-GENE-040426-2891	Length:	471	Species:	Danio rerio

Alignment Length:	446	Identity:	122/446 - (27%)
Similarity:	197/446 - (44%)	Gaps:	90/446 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TFVACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGEN-LQAY 71
            :.|.|..|.|.|.|    ||:.:.|..|.|:||....:::..|  |:||:|.::.:...| |..|
Zfish    11 SLVLCHVAFSMEMA----CYFTNWSQYRPGIGKYTPANVDPYL--CTHLIYAFSIINQRNELVTY 69

  Fly    72 SMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAY 136
            ..|:. .:|| .|:|   ||.|.|.||.||:|||     .:..:....::......:..||:|..
Zfish    70 EWNDE-TLYK-AFNE---LKNKNPTLKTLLAVGG-----WNFGSAQFSIMVSNPANRKTFIQSTI 124

  Fly   137 DLVKTYGFDGLDLAYQFP--KNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRD 199
            ..::|:|||||||.:::|  :..|.:                            .|::||.|.::
Zfish   125 KFLRTHGFDGLDLDWEYPGARGSPPE----------------------------DKQRFTLLCKE 161

  Fly   200 VKDSLRADGFL-----LSLTVLPNVNSTWY---FDIPALNGLVDFVNLATFDFLTPARNPEE--A 254
            :..:..|:...     |.||...:......   ::|..:...::|:|:.|:||    ....|  .
Zfish   162 LVAAYEAESKATGNPQLMLTAAVSAGKGTIDDGYEIAEIAKYLNFINVMTYDF----HGTWERFT 222

  Fly   255 DYSAPIYHPDGSKDR--LAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVV 317
            .:::|:|  .||||.  |.:.|.|:.:.||...|.|..|:.:|.|.||..::||......|.|
Zfish   223 GHNSPLY--QGSKDEGDLIYFNTDYAMRYWRDNGTPVEKLRMGFAAYGRTFRLTSSDTSVGAP-- 283

  Fly   318 PETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQI 382
              .||||..|..:::.|..||.||||.|.....|::...:.|               |...:.:
Zfish   284 --ASGPASAGTYTREAGFWSYYEICGFLEGTTIQWIDDQKVP---------------YATKNSE- 330

  Fly   383 TEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPILRAIK 437
                ||.:|..:|...|..|.:.||.||..::.|..|||.|| ||...:|::..::
Zfish   331 ----WVGFDTKESYETKVRYLKDKNFGGAFVWALDLDDFAGQFCSQGNHPLMAHLR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	116/431 (27%)
chia.3	NP_998378.1	Glyco_18	24..363	CDD:214753	109/412 (26%)
		GH18_chitolectin_chitotriosidase	25..385	CDD:119351	116/428 (27%)
		ChtBD2	421..469	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592078
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840