DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and chia.2

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	440	Identity:	122/440 - (27%)
Similarity:	196/440 - (44%)	Gaps:	90/440 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VACLFAASTEAASNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGEN-LQAYSM 73
            |.|..|.|.|    :.||:.:.|..|.|:||....:::..|  |:||.|.:|.:...| |..|..
Zfish    13 VLCHLAFSME----MGCYFTNWSQYRPGIGKYTPANVDPFL--CTHLFYAFAMINHANELITYEW 71

  Fly    74 NENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDL 138
            |:. .:|| .|:|   ||...|||:.||:|||     .:..:....::......:..||:|:...
Zfish    72 NDE-TLYK-AFNE---LKNTNPHLRTLLAVGG-----WNFGSTQFSIMVSSAANRQTFIQSSIKF 126

  Fly   139 VKTYGFDGLDLAYQFP--KNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKEQFTALVRDVK 201
            ::||||||:||.:::|  :..|.:                            .|::||.|.:::.
Zfish   127 LRTYGFDGMDLDWEYPGSRGSPPE----------------------------DKQRFTLLCKELL 163

  Fly   202 DSLRADG-------FLLSLTVLPNVNS-TWYFDIPALNGLVDFVNLATFDFLTPARNPEE--ADY 256
            ::..|:|       .:||..|.....: ...::|..:...:||:|:.|:||    ....|  ..:
Zfish   164 EAYEAEGKATGRRRLMLSAAVSAGKGTIDDGYEIAEIAKYLDFINIMTYDF----HGTWERFTGH 224

  Fly   257 SAPIYHPDGSKDR--LAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVPE 319
            ::|:|  .||||.  |.:.|.|:.:.||...|.|..|:.:|.||||..::||......|.|
Zfish   225 NSPLY--QGSKDEGDLVYFNTDYAMRYWRDNGTPVEKLRMGFATYGRTFRLTSSDTSVGAP---- 283

  Fly   320 TSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITE 384
            .||||..|..:::.|..||.||||.|.....|::...:.|               |...:.:
Zfish   284 ASGPASAGTYTREAGFWSYYEICGFLEGTTVQWIDDQKVP---------------YATKNSE--- 330

  Fly   385 GIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQ-CSGDKYPIL 433
              ||.:|..:|...|..|.:.|..||..::.|..|||.|| |....:|::
Zfish   331 --WVGFDTKESYETKVRYLKDKKFGGAFVWALDLDDFAGQFCGQGNHPLM 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	117/427 (27%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	117/426 (27%)
		Glyco_18	24..363	CDD:214753	110/408 (27%)
		CBM_14	423..468	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940