DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and Idgf6

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	250/447 - (55%)
Similarity:	315/447 - (70%)	Gaps:	20/447 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 VACLFAASTEAA---------SNLVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRG 65
            :..|..||.:|:         .:|||||||:|:.:||||||:..:||.|||||.:|||||||:..
  Fly     8 IVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGYAGIER 72

  Fly    66 ENLQAYSMNE--NLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDH-----PNKYIDLLEG 123
            ::.:|.|:|:  :||:.|..:..||.||||||::|:|||||||.||:.|.     ||||::|||.
  Fly    73 DSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYLELLES 137

  Fly   124 EKVRQIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAAL 188
            ...| ..|:.:.|.|||||||||||:|:|||||||:|||..:|..||..||:|:||.|||..:..
  Fly   138 PTGR-TRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDEKSEE 201

  Fly   189 HKEQFTALVRDVKDSLRADGFLLSLTVLPNVNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEE 253
            ||||||||:||||::.|.|..|||.||||||||:.::||||:...:|||||.||||.||.||||.
  Fly   202 HKEQFTALLRDVKNAFRPDNLLLSTTVLPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQRNPEV 266

  Fly   254 ADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLEGVPVVP 318
            |||:||||.   ..:|....|...||:|||....|::|||:||||||..||||.|||..|||.|.
  Fly   267 ADYAAPIYE---LSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDSGDTGVPPVK 328

  Fly   319 ETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQIT 383
            :....||.|..:|.||:.|:.|:|..|.|..|.:|||..:||.:|.||.||||..|||..|.:..
  Fly   329 DVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYAYRAADKKGD 393

  Fly   384 EGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSGDKYPILRAIKYRL 440
            .|||||::|||:|::||.|.|.:|||||||||||||||||.|:.:||||||||||||
  Fly   394 NGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYRL 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	244/423 (58%)
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	244/423 (58%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	227/401 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469721
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850