DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf2 and Cht10

DIOPT Version :9

Sequence 1:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	125/422 - (29%)
Similarity:	209/422 - (49%)	Gaps:	70/422 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LVCYYDSSSYTREGLGKLLNPDLEIALQFCSHLVYGYAGLRGENLQAYSMNENLDIYKHQFSEVT 88
            ::||:.:.::.|:|:|: ..|| :|..:.|:|::||:|.|....|...:.:...|:..:.::.||
  Fly   967 VICYFTNWAWYRKGIGR-FTPD-DINTELCTHVIYGFAVLDYSELVLRTHDSWADVENNFYTRVT 1029

  Fly    89 SLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVRQIGFIRSAYDLVKTYGFDGLDLAYQF 153
            |||.|  .:||.|::||.:|...|   ||..|:.....|. .|:|.|.:.::.|||:||||.:::
  Fly  1030 SLKSK--GIKVSLALGGWNDSQGD---KYSRLVRSPMARS-RFVRHALEFIEKYGFEGLDLDWEY 1088

  Fly   154 PKNKPRKVHGDLGLAWKS-IKKLFTGDFIVDPHAALHKEQFTALVRDVKDSLRADGFLLSLTVLP 217
            |            :.|:: ..|..|.:          |:.|||.|:::.::.|..|.:||..|.|
  Fly  1089 P------------VCWQTECNKGSTEE----------KDGFTAWVQELSEAFRPRGLMLSTAVSP 1131

  Fly   218 N---VNSTWYFDIPALNGLVDFVNLATFDFLTPARNPEEADYSAPIY-HPDGSKDRLAHLNADFQ 278
            :   :::.  :|||.|:...|::.:.|:||  .....::..:.||:| |||   |...:.|.::.
  Fly  1132 SRKIIDAG--YDIPQLSRYFDWIAVMTYDF--HGHWDKKTGHVAPLYHHPD---DDFEYFNVNYS 1189

  Fly   279 VEYWLSQGFPSNKINLGVATYGNAWKL--TKDSGLEGVPVVPETSGPAP--EGFQSQKPGLLSYA 339
            :.||:.:|.||.|:.:|:..||.::.|  |..|||       ....|||  .|..::..|.|:|.
  Fly  1190 INYWMEKGAPSQKLVMGIPLYGQSFTLENTNSSGL-------NAKAPAPGEAGEFTRAAGFLAYY 1247

  Fly   340 EICGKLSNPQNQFLKGNESPLRRVSDPTKRFGGIAYRPVDGQITEGIWVSYDDPDSASNKAAYAR 404
            |||.::          |....:.|.|...|.|..||:...       |||||.||....|:...|
  Fly  1248 EICERV----------NRQGWQVVHDEFGRMGPYAYKGTQ-------WVSYDSPDMVRKKSLLVR 1295

  Fly   405 VKNLGGVALFDLSYDDFRGQCSGDKYPILRAI 436
            ...|||..::.|..|||:.:|....:|:|..|
  Fly  1296 SLKLGGGMVWALDLDDFKNRCGNGVHPLLTEI 1327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	125/422 (30%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	118/403 (29%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	125/422 (30%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840